Carcinoma =
Skin or tissue that Linda or covers internal organs
Sarcoma =
Bone, cartilage, fat, muscle, blood vessels, connective or supportive tissue
Leukemia =
Starts in blood forming tissue, bone marrow, causes large numbers or abnormal cells to produce and enter blood
Lymphoma and MM =
Immune system
CNS cancers =
Tissues of brain and spinal cord
Adjuvant tx =
“Added to”
Ex) chemo following surgery
Neoadjuvant =
Thx given before main thx
Ex) chemo to shirking tumor before surgery
Response Grading
1) Complete Response =
2) Partial Response =
3) Progressive Disease =
4) Stable Disease =
1) Disappearance of all target lesions for at least one month
2) 30% reduction in sum of diameters of target lesions compared to baseline
3) 20% increase in the sum of diameters of target lesions
4) Unable to meet criteria for either partial response or progressive disease
Well differentiated vs.
Poorly differentiated
Looks more like normal cells, grows more slowly
Tumor that resembles the original tissue to a lesser extent