Chapter 9: Cardiac Muscle Flashcards

1
Q

Cardiac muscle is under the control by the ___ nervous system

A

autonomic nervous system

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2
Q

Is cardiac muscle neurogenic or myogenic

A

myogenic through pace maker potentials.

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3
Q

If cardiac muscle is myogenic, what is the role of the autonomic nervous system then?

A

although cardiac muscle can contract on its own, the nervous system modifies contraction, can excite or inhibit, and can contribute to gradation

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4
Q

What is the general speed of myosin ATPases in cardiac muscle? (and thus speed of contraction)

A

slow

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5
Q

What is the means by which cardiac gradation is accomplished`

A

varying length of fibers (depending on extent of the filling of the heart chambers) and varying cytosolic Ca2+ concentration through autonomic, hormonal and local metabolite influence.

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6
Q

2 Unique characteristics of cardiac muscle

A

1) cardiac fibers are joined together in a branching network 2) action potentials have a much longer duration before repolarizing due to calcium influx while K+ is effluxing, prevents the cell from going back to negative polarization as fast.

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7
Q

cardiac muscle fibers branch adn are interconnected by ___ ___

A

intercalated disks

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8
Q

Why do we need circulatory systems?

A

1) simple diffusion takes too long 2) larger animals have thicker bodies and higher metabolic rates 3) circulatory systems overcome the slowness of diffusion and allow for much faster bulk transport.

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9
Q

3 distinct components of a circulatory system

A

1) fluid: blood or hemolymph, which carries the molecules and cells than need to be transported 2) pump: dedicated pumps are called hearts; moves the fluid 3) vessels: vascular components that carry the fluid between the pump and body tissue.

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10
Q

2 broad categories of circulatory systems

A

1) open systems 2) closed system

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11
Q

explain an open system. What organisms use them?

A

a circulatory system in which HEMOLYMPH moves vvia pumping through vessels that open into an extracellular space among the tissues. Tissues are bathed in fluid and directly exchange molecules with cells. The fluid may be moved by cilia or hearts around the tissue, and vessels (arteries) typically drain the hemolymph back to starting point Found in most mollusks and all arthropods.

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12
Q

What is a hemocoel? what can it be divided into?

A

a hemocoel is used in an open circulatory system and is the entire space that is filled with hemolymph. It may be subdivided into sinuses.

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13
Q

In an open system, hemolymph flows from the pump through an ___ into the ___ (a space among the tissues), and drain from the _____ through a ___ back to the pump.

A

In an open system, hemolymph flows from the pump through an ARTERY into the HEMOCOEL (a space among the tissues), and drain from the HEMOCOEL through a VEIN back to the pump.

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14
Q

explain a closed circulatory system

A

BLOOD (rather than hemolymph) exits a heart throguh vessels that are continuous all the way back to the heart. -vessels branch and become smaller until they become tiny leaking capillaries and molecules can be directly exchanged with cells - vessel s that merge and become larger before going back to the heart.

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15
Q

2 primary components of a circulatory fluid (either blood or hemolymph)

A

1)plasma: mostly water containing dissolved and dispersed plasma proteins 2) cellular elements: hemolymph/blood cells, leukocytes etc.

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16
Q

Outline the four different types of pumping mechanisms

A

1) flagella 2) extrinsic/ skeletal muscle pumps 3) peristaltic musclar pumps 4) chamber muscle pumps.

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17
Q

How do flagella act as a pump

A

they portrude out of epithelial cells and beat slowly to create a slow current. seen in sponges.

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18
Q

How does extrinsic skeletal muscle act as a pump? Give an example. What must the animal be doing in order for skeletal muscle to act as a pump?

A

because motion of muscles or skeletal elements which are NOT apart of the normal circulatory system can move fluids. This can usually only occur during locomotion. Therefor, the animal usually needs to be moving. Seen in legs of tall animals: blood flow is aided by active skeletal muscles squeezing blood through one-way valves in veins, and by the action of the respiratory muscles in breathing.

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19
Q

How do peristaltic muscle pumps function? what is the other name for this type of pump?

A

perstaltic aka TUBULAR muscle pumps. Occurs when muscles in the WALLS of vessels contract in a moving wave that pushes fluid in FRONT of it. Allows for unidirectional fluid flow.

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20
Q

At what point are peristaltic muscle pumps called hearts?

A

they are called hearts if they occur in specialized sections of vessels.

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21
Q

compared to peristaltic muscle pumps, how to chambered muscle pumps prevent backflow?

A

peristaltic muscle pumps can contract in such a way that the fluid only moves one way. However, chambered pumps need VALVES to create flow in one direction to prevent back flow when the pump relaxes.

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22
Q

2 primary chambers in a chambered pump system

A

1) atrium: collects returning fluid 2) ventricle: provides the primary force for outgoing fluid.

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23
Q

most animals have a primary ____ heart that provides the initial force, and an auxillary pump, that does what?

A

most animals have a primary SYSTEMIC heart that provides the initial force, and an auxillary pump that AIDS FLOW RETURNING TO THE PRIMARY HEART OR FLOW GOING TO CRITICAL ORGANS.

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24
Q

Example of an auxillary pump

A

in bees, they have a PULSATILE ORGAN that boosts flow to their wings.

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25
Q

comparative heart anatomy: crustaceans, insects, and arachnids have hearts that are located in the ___ region of the body.

A

DORSAL.

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26
Q

In major arthropod groups, each hear has a porelike opening called an ____ that usually has a one way valve. What is its function?

A

They usually have OSTIUM, allows hemolymph to reenter the heart after passing through the body.

27
Q

Comparative heart anatomy: Heart differences between major arthropod groups?

A
  • larger crustaceans have a SINGLE chamber pump, whereas insects and arachnid hearts are TUBULAR (basically are just modified vessels) and can use peristaltic pumping.
28
Q

Basic structure of a primitive systemic vertebrate heart

A

a 2 chambered heart: one atrium and one ventricle.

29
Q

In fish, there are ____ primary chambers, and ___ auxillary chambers.

A

2 primary chambers (Atrium and ventricle) , 2 auxillary chambers (sinus venosus and bulbis/conus arteriosis).

30
Q

In fish, blood enters a chambered extension of the atrium called the ___ ___. Whats its function?

A

blood enters a chambered extension of the atrium called the SINUS VENOSUS; collects blood from the veins before entering the atrium.

31
Q

In fish, blood leaving the VENTRICLE first enters a chambered extension called the ___ ___ in CARTILAGINOUS FISH, or ___ ____ in BONY FISH.

A

In fish, blood leaving the VENTRICLE first enters a chambered extension called the CONUS ARTERIOUS in CARTILAGINOUS FISH, or BULBUS ARTERIOSUS in BONY FISH.

32
Q

Purpose of the conus arterious or bulbus arteriosus ?

A

these areas a fourth chambers in fish that extend from the ventricle. They help to dampen the pulsatile pressure output of the ventricle (a function taken over by the aorta in reptiles)

33
Q

See notebook for a diagram of fish (ELASMOBRANCH) heart. What is the direction of venous blood flow?

A

Venous blood enters the sinus venosus, and is then pumped by the atrium, ventricle, and bulbis cordis into the aorta.

34
Q

In air-breathing vertebrates, evolution of a separate circuit called the ___ ___ ___ occurred.

A

Pulmonary Circulation System.

35
Q

Describe the newly evolved pulmonary circulation system in air breathing vertebrates. How are the chambers for the two circulation systems separated?

A

there is a separate part of the chambered heart to move fluid (blood) from the heart to the lungs, and then from the heart to the body. There are now two primary chambers subdivided with SEPTA to support separate circulation.

36
Q

Avian and mammal hearts are ____ pumps

A

dual pumps. One is a circulatory pump to body and the other is a pump to the lungs.

37
Q

In dual pump systems, atria RECEIVE blood from ___ and ___, and ventricles PUMP blood to ___ and ____

A

In dual pump systems, atria RECEIVE blood from LUNGS and BODY, and ventricles PUMP blood to BODY and LUNGS

38
Q

___ prevents the mixing of oxygenated blood with unoxygenated blood

A

SEPTA

39
Q

blood returning from the systemic circulation enters the ___ atrium via the ___ ___ This partially deoxygenated blood flows from the ____ atrium to the ventricle, which pumps it out through the ___ ___ to the LUNGS.

A

blood returning from the systemic (BODIL) circulation enters the RIGHT atrium via the VENA CAVAE. This partially deoxygenated blood flows from the RIGHT atrium to the ventricle, which pumps it out through the PULMONARY ARTERY to the LUNGS.

40
Q

The right side of the heart pumps blood into the ____ circulation

A

pulmonary

41
Q

After being oxygenated in the lungs, the blood returns to the ___ atrium via the ____ ___. The ___ atrium pumps the oxygenated blood to the ventricle and then exits thorugh the ____ to propel the blood to all body systems.

A

After being oxygenated in the lungs, the blood returns to the LEDT atrium via the PULMONARY VEINS The LEFT atrium pumps the oxygenated blood to the ventricle and then exits thorugh the AORTA to propel the blood to all body systems.

42
Q

the left side of the heart pumps blood into the ____ circulation

A

systemic

43
Q

the pulmonary circulation is a ___-pressure, ___-resistance system, whereas the systemic circulation is a ___-pressure, ___-resistance system.

A

the pulmonary circulation is a LOW-pressure, LOW-resistance system, whereas the systemic circulation is a HIGH-pressure, HIGH-resistance system.

44
Q

Mechanism by which heart valves close

A

due to pressure differences. A forward pressure gradient (greater pressure behind the vlave) forces the valve open, whereas backward pressure gradient (greater pressure in front of the valve once all the blood has flown past the valve) forces the valve closed.

45
Q

The AV vales are located between the ___ and ___

A

between teh atrium and ventricle.

46
Q

The aortic (between left ventricle and aorta) and pulmonary valve (between right ventricle and pulmonary artery to lung) are known as ____ valves.

A

semilunar valves

47
Q

the semilunar valves are forced open when :

A

the left and right ventricular pressures EXCEED the pressure in the aorta and pulmonary ARTERIES respectively.

48
Q

closure of semilunar valves happen when the ventricles ____, resulting in a falling of ventricular ____

A

closure of semilunar valves happen when the ventricles RELAX, resulting in a falling of ventricular PRESSURE (below the aortic and pulmonary artery pressures)

49
Q

the right AV valve is aka ____, and the left AV valve is aka____, and the aortic/pulmonary valves are aka ____

A

the right AV valve is aka TRICUSPID, and the left AV valve is aka MITRAL, and the aortic/pulmonary valves are aka SEMILUNAR

50
Q

Why are there no valves between the atria and the veins (ex/ venae cava that drains de oxy blood into right atrium?)

A

1) atrial pressures are not much higher than venous pressures, resulting in insignificant backflow 2) the junctions of the veins and atria are partially compressed during atrial contraction.

51
Q

Most of the heart wall is the ____. this layer lies between the ___ and the ____.

A

Most of the heart wall is the MYOCARDIUM. this layer lies between the ENDOCARDIUM and the EPICARDIUM (outer sheath).

52
Q

the myocardium consists of interlacing bundles of ____ ___ ___

A

cardiac muscle fibers.

53
Q

individual cardiac muscle cells that interconnect to form branching fibers of the myocardium are joined to each other via specialized structures known as ___ ___

A

intercalated disks

54
Q

two types of membrane junctions in the intercalated disks

A

1) desosomes: an adhering junction that mechanically holds cells together under high mechanical struss 2) gap junctions : channels that allow action potenitals to spread from one cardiac cell to the next.

55
Q

when an AP impulse is initiated, the impulse spreads to all the other cells that are joined by gap junctions so that they can:

A

contract together as a single FUNCTIONAL SYNCYTIUM.

56
Q

what is a functional syncytium

A

a group of joined cells that act as one functional unit.

57
Q

In skeletal muscles, graded contractions can be produced by :_______. can this happen in cardiac muscle?

A

In skeletal muscles, graded contractions can be produced by VARYING THE NUMBER OF MUSCLE CELLS THAT ARE CONTRACTING WITHIN THE MUSCLE (RECRUITMENT OF MOTOR UNITS) This does not happen in cardiac muscle fibers because the muscle cells are all grouped together in a functional synctium and thus the contraction onf one cell leads to the cotnraction of others. therefore, either all cardiac muscle fibers contract or none do. You cannot have a partial contraction unless there is liek some sort of problem in the gap junction.

58
Q

a heart beat is caused by an ___ ___ that sweeps across the cardiac muscle cell membrane

A

ACTION POTENTIAL

59
Q

cardiac action potentials are generated by _____ ____ ____

A

MYOGENIC PACEMAKER CELLS (they are auto-rhthmic)

60
Q

T/F: the pacemaker cells are contractile

A

false

61
Q

What is the resting potential of the pacemaker cells?

A

they do not have a constant resting potential. the cell polarizes and depolarizes in a cyclical fashion. membrane potential slowly depolarizes until threshold potential is reached and an action potential occurs.

62
Q

What gives rise to pacemaker potentials in terms of ion movement?

A

1) an increased inward Na+ current 2) a decreased K+ efflux 3) an increased inward Ca2+ current.

63
Q

In a graphical form, outline the ion movement during a pacemaker potential.

A

During the first part of the potenital, there is Na+ influx, followed by K+ efflux reduction, resulting in a growing of positive potential in the cell. Once at threshold, voltage gated Ca2+ channels open and Ca2+ moves into the cells, causing an action potential.

64
Q
A