Chapter 4 - Regulation of Gene expression (2019) - Evals #2 by Keim Flashcards Preview

PHYSIOLOGY - 1st Year 1st Sem Comprehensive Exam > Chapter 4 - Regulation of Gene expression (2019) - Evals #2 by Keim > Flashcards

Flashcards in Chapter 4 - Regulation of Gene expression (2019) - Evals #2 by Keim Deck (43)
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1

Codes the DNA polypeptide

Exon

2

First protein that binds to the DNA

TF IID

3

Which of the following is NOT involve in translation?
a.DNA
b.mRNA
d. Protein

DNA

4

What step in gene expression with a genetic code on the mRNA is read by your tRNA and then amino acid is carried by tRNA are added in nascent
polypeptide chain?

Translation

5

All biological components of structures in the directly corresponding their
function, which of the following is the CORRECT statement regarding
chromosomal structure?

Histone and scafolds condensed DNA into a size that is fit into the nucleus.

6

Translation of the mRNA on ribosomes always begin at which codon and what amino acid it translates to:

AUG — methionine

7

True or False:

The central dogma of molecular biology states that genetic information flows UNIDIRECTIONALLY from DNA to proteins.

True

8

What is a gene?

A DNA segment that contains all genetic information required to encode RNA and protein molecules

9

A promoter is:
a. Determines the site for initiation of transcription
b. Determines Direction of transcription
C. Consists of modules of simple sequences (DNA elements)
D.ALL OF THE ABOVE

D. All of the above

10

Inhibit the activity of transcriptional activators not by interfering w/ DNA binding, but by a direct protein-protein interaction w/ activators:

Quenching

11

Liver cells perceive the presence of glucagon and stimulate PEPCK gene expression. This illustrates the phenomenon of:
a. Tissue-specific gene expression
b. Forced gene expression
c. Adaptation gene expression
d. Inducible gene expression

D. Inducible gene expression

12

A cis-acting regulatory element that is required for expression of gene.

Promoter

13

Most regulated step in gene expression:

Inititation of transcription

14

Which of the following is not true for Na/K pumps?

In most epithelial cells, the sodium pump is restricted to the apical membrane of a cell.

15

Which of the following pump runs as an ATP synthase of the inner membrane of the mitochondria? F-type ATPase

F-type ATPase

16

4. The ABC transporters can act as:

all of the above

17

Acid extruders are stimulated when the cell is acidified, and is inhibited when the cell is alkalinized, hence maintaining pH for proper cell functioning. Which of the following is NOT an acid extruder?

Calcium pumps

18

Which of the following is NOT a driving force for the Na-Glucose co-transporter?

Hydrolysis of ATP

19

Which if the following is a primary active transporter?

N/K A

20

9. The tube is separated by an impermeable membrane into two chambers. The left chamber contains 1L of 2 m sodium chloride solution. The right chamber contains 1L of 1 m sodium chloride solution. If the membrane is made permeable to water, then osmotic pressure will cause the net flux of water to go:

from right to left.

21

Which of the following is true?

Inside the cell, the quantity of positively charged ions is almost exactly equal to the quantity of negatively charged ions.

22

What protein pathway forms donut-like triads that allow the passage of ions, water and small molecules to diffuse to target cells?

Perforins

23

The major function of calmodulin in the cells is to act as:

Calcium-binding protein

24

Electrochemical driving force of potassium:
A. Close to zero
B. Somewhat positive
C. To move potassium outside of the cell
D. All of the above

D. All of the above

25

What is the potassium in the interstitium?

4.6

26

What is the chloride plasma water?

113

27

Chamber A contains 0.1 m KCl. Chamber B contains 0.01m KCl. So Chamber A is negatively charged compared to chamber B. Which of the ff. statement is correct based on the details above?

The concentration force of potassium is larger than the electrical force.

28

In the respiratory chain, F0, F1 ATPase forms complex?

V

29

These are true statements for each K-pump except:

It is a secondary acting transporter.

30

Which of the following is not an exchanger?

None of the above