Chapter 21 - Musculoskeletal And Anti-inflammatory Drugs Flashcards Preview

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Flashcards in Chapter 21 - Musculoskeletal And Anti-inflammatory Drugs Deck (9)
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1

Anti-inflammatory

(P. 403 and 584)

Medication used to relieve inflammation.

• In this chapter, anti-inflammatory drugs are used to treat disorders in which the musculoskeletal system is not functioning properly because of inflammation.

2

musculoskeletal conditions with inflammation:

(P. 403)

• arthritis
• bursitis
• spondylitis
• gout
• muscle strains
• sprains

☆ can cause swelling, redness, heat, pain, and limited muscle and joint mobility.

3

Neuromuscular blocking agents (NMBAs)

(P. 403)

Used during surgical, endoscopic, or Orthopedic procedures.

• These drugs are potentially very dangerous and can result in respiratory arrest because of potential to paralyzed the major muscle of ventilation, the diaphragm.

☆ these are administered only by anesthesiologists or specially trained Personnel skilled in intubation, medically induced paralysis, and resuscitation.

4

Nonsteroidal Anti-inflammatory Drugs (NSAIDs)

(P. 403-404)

Such as ibuprofen, inhibit the synthesis of prostaglandins, substances responsible for producing much of the inflammation and pain of rheumatic conditions, sprains, and menstrual cramps.

5

Osteoporosis

(P. 408-409)

(Porous Bone) is defined as a systemic skeletal disease characterized by low bone mass and deterioration of bone tissue, leading to Bone fragility and entry susceptibility to fracture, especially of the hip, spine, and wrist.

6

Osteoporosis therapy

(P. 408-409)

Includes calcium and vitamin D supplementation and several prescription medications currently approved for the prevention and or treatment of osteoporosis.

7

Hormone replacement therapy (HRT)

(P. 410)

Estrogen with or without progestin -- is recommended for postmenopausal osteoporosis prevention secondary to estrogen deficiency only when the patients are unable to take other agents and when the benefits outweigh risks.

• the FDA recommends prescribing the lowest possible dose for the shortest period of time.

☆ If HRT is started soon after menopause, estrogen prevents The Accelerated phase of the bone loss that occurs in the first 5 years after the onset of menopause.

8

Skeletal muscle relaxants

(P. 401 and 594)

Medications used to treat some musculoskeletal disorders associated with pain, spasms, abnormal contraction, or impaired mobility.

9

Disorders of the musculoskeletal system are rather common. Drugs used to treat such conditions may be classified into two broad categories:

(P. 400)

1. Skeletal muscle relaxants

2. Nonsteroidal Anti-inflammatory drugs (NSAIDs)