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Endocrinology Exam One > Chapter 2 > Flashcards

Flashcards in Chapter 2 Deck (25)
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1
Q

Are epinephrine and norepinephrine typically fast or slow acting hormones?

A

Fast

2
Q

From where are epinephrine and norepinephrine released?

A

Adrenal medulla

3
Q

Are thyroid hormones typically fast or slow acting hormones?

A

Slow

4
Q

Are pituitary hormones typically fast or slow acting hormones?

A

Slow

5
Q

Slower acting hormones can take about how long to achieve full effect?

A

Sometimes months

6
Q

What is the usual range for a concentration of a particular hormone?

A

Very small: 1 picogram to a few micrograms

7
Q

What is the purpose of a negative feedback system?

A

Preventing overactivity of the endocrine system and ensuring the correct level of hormone at the target cell

8
Q

Oxytocin release increasing at the time of birth is an example of what type of mechanism?

A

Positive feedback

9
Q

After birth, oxytocin levels resorting back to normal once saturated is an example of what type of mechanism?

A

Negative feedback

10
Q

Growth hormone represents what kind of cyclic pattern?

A

Circadian (daily)

11
Q

Melatonin represents what kind of cyclic pattern?

A

Seasonal (circannual)

12
Q

What can have an influence on the cyclic variation of hormones?

A

Nervous system

13
Q

What is the method of hormone transport for peptides and catecholamines?

A

Dissolve in plasma, transported to target tissues, diffuse out of capillaries into interstitial fluid to target cells (water soluble)

14
Q

What is the method of transport for steroid and thyroid hormones?

A

Circulate in blood bound to plasma protein

15
Q

When are steroid and thyroid hormones deemed inactive?

A

When bound to plasma proteins during transport

16
Q

When does the concentration of a particular hormone increase?

A

If rate of secretion is greater than clearance

17
Q

When does concentration of a particular hormone decrease?

A

If rate of secretion is less than clearance

18
Q

What is MCR?

A

Metabolic clearance rate (number of milliliters of plasma cleared of hormone per minute)

19
Q

What is the Guyton/Hall definition for metabolic clearance rate (MCR)?

A

rate of disappearance of hormone from the plasma/concentration of hormone

20
Q

What organ is responsible for clearing the system of steroid hormones?

A

Liver

21
Q

What does the liver do to clear the system of hormones?

A

Conjugates them and excretes them in bile

22
Q

What condition could lead to high amounts of hormones staying present in the system?

A

Diseased liver

23
Q

Where can hormone receptors be located?

A

On/in the cell membrane, in the cell cytoplasm, in the nucleus

24
Q

The formation of what substance is used by hormones to exert intracellular actions?

A

Second messengers (cAMP)

25
Q

What is the function of cAMP in hormone regulation?

A

Activation of a single type of membrane receptor