Chapter 16 Pharmacology Flashcards Preview

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Flashcards in Chapter 16 Pharmacology Deck (73)
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1

Scientists who study how drugs interact with living systems are known as:

Pharmacologist

2

In research setting, experimental drugs are also known as:

test articles

3

Pharmacologists use what discipline to study how a drug is handled by the body?

Pharmacokinetics

4

What is the term used for the amount of drug administered that produces the desired pharmacological effect without producing toxicity?

Therapeutic dose

5

Formulary dosages are best interpreted as:

recommendations

6

A drug compound will affect two animals in the same way, regardless of sex or health status, if the dose is equivalent.

False

7

The four processes by which a drug is handled by the body -absorption, distribution, metabolism, and excretion- are the focus of which discipline?

Pharmacokinetics

8

Only the metabolites of a drug are eliminated by excretion.

False

9

What term is used for the ability of a drug to enter the bloodstream from the site of administration?

Absorption

10

What organ is a major site of drug metabolism?

Liver

11

In what order, from fastest to slowest, in time it takes for a drug administered to take effect in the body?

IV>IP>IM>SQ>PO

12

What does ADME stand for?

Administer, Distribution, Metabolism, Excretion

13

The breakdown products of drugs are called ?

metabolites

14

What are the types of drug interaction?

Synergistic
Antagonistic
Potentiation
Additive

15

Why is clauvanate administered with amoxicillin?

To overcome breakdown of the antibiotic.

16

A drug interaction that results in reduced effect of one or both drugs is called:

Antagonistic

17

The liver excretes drugs and drub metabolites into the bile.

True

18

All drugs are toxic if given in excess.

True

19

The therapeutic index is a ratio that compares an effective does to a:

toxic dose

20

The therapeutic index can be expressed as the effective dose(ED50) divided by the lethal dose (LD50).

False: the therapeutic index is expressed as the lethal dose in half of a test population (LD50) divided by the effective dose in half to a test population (ED50).

21

In multimodal drug therapy, drugs with different mechanisms of action are combined.

True

22

What is the term for the quantity of the drug per unit of body weight?

Dose rate

23

Dosage regimen includes:

Dose, route of administration, frequency of administration, duration

24

Clinical signs of adverse drug effects are similar regardless of the body system affected.

False

25

Controlled substances are classified in how many schedules?

5

26

Who establishes the expiration date of an FDA-approved drug?

Drug manufacturer

27

Product labeling includes information contained on the shipping label.

True

28

One should never exceed the drug dosage recommended by the manufacturer for the animal species to be treated.

False

29

What is needed to obtain controlled substances in an animal facility?

Federal and/or state licenses

30

The symbol required for the label of a controlled drug contains a capital "X" and an Arabic number.

False: The symbol for a controlled drug contains a capital "C" and a Roman numeral.