Flashcards in Chapter 16 Pharmacology Deck (73)
Scientists who study how drugs interact with living systems are known as:
In research setting, experimental drugs are also known as:
Pharmacologists use what discipline to study how a drug is handled by the body?
What is the term used for the amount of drug administered that produces the desired pharmacological effect without producing toxicity?
Formulary dosages are best interpreted as:
A drug compound will affect two animals in the same way, regardless of sex or health status, if the dose is equivalent.
The four processes by which a drug is handled by the body -absorption, distribution, metabolism, and excretion- are the focus of which discipline?
Only the metabolites of a drug are eliminated by excretion.
What term is used for the ability of a drug to enter the bloodstream from the site of administration?
What organ is a major site of drug metabolism?
In what order, from fastest to slowest, in time it takes for a drug administered to take effect in the body?
What does ADME stand for?
Administer, Distribution, Metabolism, Excretion
The breakdown products of drugs are called ?
What are the types of drug interaction?
Why is clauvanate administered with amoxicillin?
To overcome breakdown of the antibiotic.
A drug interaction that results in reduced effect of one or both drugs is called:
The liver excretes drugs and drub metabolites into the bile.
All drugs are toxic if given in excess.
The therapeutic index is a ratio that compares an effective does to a:
The therapeutic index can be expressed as the effective dose(ED50) divided by the lethal dose (LD50).
False: the therapeutic index is expressed as the lethal dose in half of a test population (LD50) divided by the effective dose in half to a test population (ED50).
In multimodal drug therapy, drugs with different mechanisms of action are combined.
What is the term for the quantity of the drug per unit of body weight?
Dosage regimen includes:
Dose, route of administration, frequency of administration, duration
Clinical signs of adverse drug effects are similar regardless of the body system affected.
Controlled substances are classified in how many schedules?
Who establishes the expiration date of an FDA-approved drug?
Product labeling includes information contained on the shipping label.
One should never exceed the drug dosage recommended by the manufacturer for the animal species to be treated.
What is needed to obtain controlled substances in an animal facility?
Federal and/or state licenses