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Flashcards in Chapter 14 Deck (48)
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1

What are Neutrophils?

Granulocytes 

Most abundant WBC

Performs phagocytosis of foreign particles

Increased numer during acute a bacterial infeciton 

1

Describe the components of plasma?

Blood plasma is composed of 2 parts:

  • Water
  • Solutes (plasma proteins, nutrients, wastes, gases, electrolytes)

2

What does Thrombopoietin do?

Increase the number of platelet precursors

2

What is the function  of hemoglobin?

Hemoglobin is a protein in red blood cells that carries oxygen and some carbon dioxide. 

Composed of 4 globular protein chains (globin) and a heme group, centered around an Fe molecule. 

2

What are the 3 main plasma proteins?

  1. Albumin
  2. Globulin
  3. Fibrinogen

3

What is leukocytosis?

A increases in the number of white blood cells

 

4

What does Cytokines do?

Increase the number of WBC precursors. 

5

What do Lymphoid stem cells give rise to?

Agranular lymphocytes (T and B-cells) 

5

What are the 2 primary functions of albumin?

  1. Maintenance of osmotic pressure
  2. Transportation of free fatty acids, hormones, and bilirubin

6

Describe the antigens and antibodies involved in ABO blood type group.

Antigens A and B determine blood type.

Plasma contains antibodies designed as anti-a and anti-b that react with antigen that are foreign 

7

What two lines of stem cells does Hemocytoblasts give rise to?

Myeloid Stem cells

Lymphoid stem cells 

7

What are Lymphocytes? 

Agranulocytes

Cells live for an extended period of time

Produce antibodies 

Increase during viral and bacterial infection. 

 

8

What do Myleoid stem cells give rise to?

Erythrocytes, platelets, granular leukocytes, and agranular monocytes. 

8

What are Basophilis? 

Granulocytes

Realse Haprin and Histamine 

Can develop into mast cells.

Allergy mediators 

9

What is hemostasis?

The stoppage of bleeding

11

What are the three types of cells that comprise formed elements?

1. Erythrocyes (Red Blood Cells)

2. Leukocytes (White Blood Cells)

3. Thrombocytes (Platelets) 

11

What would a decreased hematocrit indicate?

Anemia: A decrease in number of RBC

 

13

What are Neutrophils and their functions?

They are Granulocytes 

Most abundant WBC 

Preform phagocytosis of foreign particles 

Increased number during bacterial direction. 

16

Describe the Rh Blood group and the antigens and antibodies involved. 

Rh antigen are classified as Rh+

Those who lack the antigen are Rh-

17

What is clotting factor II a?

Thrombin

18

List the three functions of blood.

1. Transportation of gases, nurtients,waste, and hormones

2. Regulation of pH, temp. and water

3. Protection through clotting, and combating microbes with phagocytes and plasma protein. 

 

20

Describe the extrinsic pathway for blood

  • Initiated by tissue damage which leads to the release of Tissue thromboplastin (III)
  • Factors involved include VII, X, and V.
  • Leads to the release of Prothrombin activator.

21

What clotting factor is III ?

Tissue thromboplastin

22

Describe the process of erythropoiesis.

Low O2 causes the kidneys and live to release erythrpoietin (EPO) into the bloodstream where it travels to red bone marrow and stimulates production of RBC that carry O2 to tissues. 

23

What is a reticulocyte count?

A test used to indicate the rate of erythropoiesis (normal range 0.5 - 1.5%) 

Abnormally high reticulocyte count suggests anemia. 

24

What is fibrin?

The insoluble protein that leads to the actual clot.

25

Describe the breakdown of RBC and hemoglobin. 

(Page 529)

25

What are the functions of platlets?

To function to stop blood loss from damaged vessels by

forming a platelet plug.

26

What would a increaed hematocrit indicate?

Polycythemia: a increase in RBC, seen in atheletes that are blood doping. 

27

What is a thrombosis?

  • Thrombosis – clotting in an unbroken blood vessel.