Ch 35 Nonopioid Analgesics Flashcards Preview

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Flashcards in Ch 35 Nonopioid Analgesics Deck (4)
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0

What's the overview of NONOPIOD drugs

NONOPIOD analgesics may have an anti inflammatory, antipyretic and analgesic action. These meds include non steroidal anti inflammatory drugs and acetaminophen

1

NSAIDS

Cox 1 and cox 2 inhibitors
Aspirin
Ibuprofen ( Motrin, Advil, IV preparations include caldolor, NeoProfen)
Naproxen (naprosyn) naproxen sodium ( aleve)
Indomethacin ( Indocin)
Diclofenac ( oral forms- voltaren, cataflam, zipsor; intradermal forms- Flector patch, Pennsaid, voltaren gel)
Ketoconazole ( generic, Sprix, an intranasal form)
Meloxicam ( mobic)

2nd generation;
Celecoxib ( Celebrex)

2

What's the expected pharmalogical action of NSAIDS

Inhibition of cyclooxygenase- inhibition of COX 1 can result in decreased platelet aggregation and kidney damage. Inhibition of cox 2 results in decreased inflammation, fever, and pain

3

What are the therapeutic uses of NSAIDS

Inflammation supression
Analgesia for mild to moderate pain such as osteoarthritis and rheumatoid arthritis
Fever reduction
Dysmenorrhea
Inhibition of platelet aggregation which protects against ischemic stroke and MI