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Flashcards in Cellular Response to Stress Deck (10)
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1
Q

Nuclear changes in necrosis

A

Pyknosis –> Karyorrhexis –> karyolysis

2
Q

Pubertal breast changes is an example of physiologic ____ (hyperplasia/hypertrophy)

A

Hyperplasia

3
Q

Architecture is not preserved in this kind of necrosis

A

caseous

4
Q

In intrinsic pathway of apoptosis, BCL2 is ____ (activated, inactivated) while BAX/BAK channel is ____ (activated, inactivated)

A

Inactivated BCL2

Activated BAX/BAK

5
Q

Caspase 8 and 10 are initiator caspases of which apoptotic pathway

A

Extrinsic

Intrinsic: Caspase 9

6
Q

Executioner caspases are caspase ___ and ____

A

3 and 6

7
Q

Intracellular hyaline that is PAS positive, diastase resistant is a characteristic of ___ disease

A

alpha 1 antitrypsin deficiency

8
Q

PAS postive, diastase-sensitive glycogen granule in hepatocyte is characteristic of what disease?

A

DM

9
Q

Onchronosis is due to the endogenous production of

A

Homogentisic acid (alkaptonuria)

10
Q

Enzymes that are adapted to food deprivation, increases cellular longevity, and activation of DNA repair mechanism

A

sirtuins