Cell as a Unit of Health and Disease Flashcards Preview

pathology > Cell as a Unit of Health and Disease > Flashcards

Flashcards in Cell as a Unit of Health and Disease Deck (41)
Loading flashcards...
31

Growth factor: chemotactic for neutrophils, fibroblasts, and smooth muscles, and activates proliferation of fibroblasts and endothelial cells.

Platelet-derived growth factor (PDGF) (VEGF)(TOPNOTCH)Robbins Basic Pathology, 9th ed. p. 19

32

Growth factor: chemotactic and mitogenic for fibroblasts and stimulates angiogenesis and ECM protein synthesis

Fibroblast growth factors (FGFs) (VEGF)(TOPNOTCH)Robbins Basic Pathology, 9th ed. p. 19

33

Component of ECM responsible for the ability of tissues to recoil and recover their shape after physical deformation.

Elastin(TOPNOTCH)Robbins Basic Pathology, 9th ed. p. 23

34

Component of ECM that confer resistance to compressive forces, also provide lubrication between bony surfaces.

Proteoglycan(TOPNOTCH)Robbins Basic Pathology, 9th ed. p. 23

35

The most abundant glycoprotein in basement membrane.

Laminin(TOPNOTCH)Robbins Basic Pathology, 9th ed. p. 24

36

A major component of the interstitial ECM.

Fibronectin(TOPNOTCH)Robbins Basic Pathology, 9th ed. p. 24

37

A large family of transmembrane glycoproteins that allow cells to attach to ECM constituents, linking the intracellular cytoskeleton with the outside world.

Integrins(TOPNOTCH)Robbins Basic Pathology 9th ed. p. 24

38

Sequence of events in cell cycle

G1/Presynthetic growth-S/DNA synthesis-G2/Premitotic growth- M/mitotic phase (TOPNOTCH) Robbins Basic Pathology, 9th ed., p.25

39

Two important properties of stem cells

Self-renewal and assymetric division. (TOPNOTCH) Robbins Basic Pathology, 9th ed., p. 26

40

Most undifferentiated stem cells which are totipotent, and can be induced to form specialized cells of all three germ cell layers.

Embryonic stem cells(TOPNOTCH)Robbins Basic Pathology, 9th ed. p. 27

41

Variety of stem cell with limited repertoire of differentiated cells that they can generate.

Tissue stem cells(TOPNOTCH)Robbins Basic Pathology, 9th ed. p. 27

Decks in pathology Class (48):