CBC, Peripheral Blood and Marrow, and Hematopoiesis Flashcards Preview

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Flashcards in CBC, Peripheral Blood and Marrow, and Hematopoiesis Deck (54)
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1

____ stimulates basophil production

IL-3

2

____ stimulates eosinophil production

IL-5

3

_______ are anucleate cells in the erythroid lineage

reticulocytes and erythrocytes

4

_______ lineage: _______ -> basophilic normoblast -> polychromatophilic normoblast -> orthochromatic normoblast -> _______ -> _______

Erythroid; Pronormoblast; reticulocyte; erythrocytes

5

_______ lineage: Myeloblast -> promyelocyte -> myelocyte -> metamyelocyte -> ______ -> ______

Granulocyte; band; segmented -----phil

6

A pale blue inclusion at the periphery of a RBC consisting of condensed RNA is described as _______

Dohle Body

7

Average lifetime of erythrocytes in the peripheral blood

120 days

8

Average lifetime of monocytes in the peripheral blood before becoming macrophages in tissues

20 days

9

Average lifetime of neutrophils in the peripheral blood

7-10 hours

10

Average lifetime of platelets in the peripheral blood

8-9 days

11

Childhood levels of HGB and HCT are _______ than those of adults

lower

12

Denatured/oxidized hemoglobin attached to the inner side of the cell membrane is described as _______.

Heinz Bodies

13

Erythroid lineage: _______ -> basophilic normoblast -> _______ -> orthochromatic normoblast -> reticulocyte -> erythrocytes

Pronormoblast; polychromatophilic normoblast

14

Erythroid lineage: Pronormoblast -> _______ -> polychromatophilic normoblast -> orthochromatic normoblast -> _______ -> erythrocytes

basophilic normoblast; reticulocyte

15

Erythroid lineage: Pronormoblast -> _______ normoblast -> _______ normoblast -> _______ normoblast -> reticulocyte -> erythrocytes

basophilic; polychromatophilic; orthochromatic

16

Female HCT

36-47%

17

Female normal concentration of RBCs

4.2-5.6x10^12/L

18

Female normal HGB

12.1-16.3g/L

19

Granulocyte lineage: _______ -> promyelocyte -> myelocyte -> metamyelocyte -> _______ -> segmented -----phil

Myeloblast; band

20

Granulocyte lineage: Myeloblast -> _______ -> myelocyte -> _______ -> band -> segmented -----phil

promyelocyte; metamyelocyte

21

IL-3 stimulates ______ production

basophil

22

IL-5 stimulates _______ production

eosinophil

23

In bone marrow, the ratio of granulocytic:erythroid precursors should be about ____.

3 to 1

24

In the erythroid lineage, the ability to replicate is lost at progession to the _______ stage.

Orthochromic normoblasts

25

In the granulcyte lineage, the last cell with replicative ability is the _______

myelocyte

26

In the granulocyte lineage, primary granules first appear in the ______ stage.

promyelocyte

27

In the granulocyte lineage, the largest cell is the _____

promyelocyte

28

In the megakaryocyte lineage, endoreduplication begins in the _____ stage.

promegakaryocyte

29

Male HCT

39-50%

30

Male Normal concentration of RBCs

4.75-6.1x10^12/L