Cardiovascular Pharmacology Flashcards Preview

Year 2 > Cardiovascular Pharmacology > Flashcards

Flashcards in Cardiovascular Pharmacology Deck (12)
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1
Q

When is ANP and BNP released by the atria and ventricles

A

Stretching of walls
Increased pressure
Overload

2
Q

What does ANP and BNP do in the body

A

Increase renal excretion of water and sodium

Vasodilation

3
Q

What enzyme metabolises ANP and BNP

A

Neutral endopeptidases (inhibit these and this will increase plasma BNP and ANP levels - good for pharmacological study!)

4
Q

When are nitrates given

A

Angina
Heart Failure

GTN

5
Q

Adverse effects of nitrates

A

Headaches

6
Q

First-line treatment for angina

A

Beta-blocker or calcium-channel blocker

7
Q

What else is given for angina control

A

Aspirin + clopidogrel

Statins

GTN for acute attack

8
Q

Anti platelet therapy for ACS

A

Aspirin + Clopidogrel

9
Q

Antithrombin therapy for ACS

A

Fondaparinux

10
Q

High risk cases for ACS medications

A

IIb/IIIa inhibitors

11
Q

What are Class IV drugs

A

Calcium channel blockers

12
Q

Amiodarone adverse effects

A

QT prolongation
Ventricular tachycardia
Hypothyroidism
Optic neuropathy

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