Brachyspira Flashcards Preview

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Flashcards in Brachyspira Deck (28)
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1
Q

Brachyspira and Treponema are known as ____

A

spirochetes

2
Q

Brachyspira belongs to the family ____ and are obligate _____

A

family Spirochaetaceae

Obligate anaerobes

3
Q

what part of the body does Brachyspira colonize?

A

large intestine

*mainly colon

4
Q

What is the most important species of Brachyspira?

A

Brachyspira Hyodyseneriae

5
Q

What does Brachyspira hyodysenteriae cause and in what animal?

A

Swine Dysentery

*affects actively growing pigs

6
Q

What makes the Brachyspira cell wall different?

A

has a lipo-oligosaccharide

7
Q

Brachyspira contains Hemolysin. The more ____ the bacteria, the more chance that it will be associated with bad disease

A

hemolytic

8
Q

Brachyspira Hyodysenteriae is strongly ____ hemolytic

A

beta

9
Q

What virulence factor is necessary for Brachyspira and allows the bacteria to move through intestinal mucosa?

A

flagella

10
Q

What are the most important reservoir for Brachyspira hyodysenteriae?

A

asymptomatic carrier pigs

11
Q

How is Brachyspira transmitted?

A

fecal-oral

12
Q

what is the pathogenesis for Brachyspira?

A

edema, hypermia, hemorrhages

if the infection is bad enough it can lead to failure of colonic absorption

13
Q

What is the major clinical sign of Brachyspira?

A

Diarrhea

*normally bloody because of damage to enterocytes

14
Q

What are the differentials for Brachyspira Hyodysenteriea that are hard to differentiate?

A

Salmonellosis and Lawsonia intracellularis

15
Q

What species of Brachyspira causes avian intestial spirochaetosis?

A

B. pilosicoli

16
Q

Fecal samples for diagnosis of Brachyspira should not be allowed to ___

A

dry out

17
Q

What is the special blood agar for Brachyspira?

A

BJ agar

*specific agar with several antibiotics incoorporated

18
Q

The more virulent the strain of Brachyspira, the more ____ on blood agar

A

hemolytic

19
Q

What disease does Lawsonia Intracellularis cause?

A

proliferative enteropathy

*in many different species, but mainly porcine

20
Q

Lawsonia intracellularis are ____intracellular pathogens of enterocytes

A

obligate

21
Q

What type of secretion system does Lawsonia have?

A

Type 3

22
Q

What are the reservoirs for Lawsonia?

A

intestinal tract and environment

23
Q

How is Lawsonia transmitted?

A

fecal oral route

24
Q

what is requires for Lawsonia to be infective?

A

interaction with unknown natural flora are required for disease

*If the animal has no bacteria in the GI tract then Lawsonia cannot cause disease

25
Q

Lawsonia inhibits the host cell ____ process

A

maturation

*leads to more bacterial cells and proliferative lesions in the enteric mucosa

26
Q

What antibody is predominant in Lawsonia infections?

A

IgA

27
Q

True/False: vaccines work well against Lawsonia

A

True

*vaccines and antibiotics are effective against lawsonia

28
Q

What bacteria causes rabbit syphilis?

A

Treponema Paraluiscuniculi