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Flashcards in Bordetella Deck (31)
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1
Q

Bordetella causes kennel cough and ____ in swine

A

atrophic rhinitis

2
Q

Bordetella are aerobic bacteria that infect the ______ of hosts

A

ciliated respiratory epithelium

3
Q

Which Bordetella species have flagella?

A

Bordetella bronchiseptica and B. avium

4
Q

True/False: Bordetella is highly variable

A

True

difficult for vaccination

5
Q

Which species of Bordetella causes porcine atrophic rhinitis and Canine kennel cough?

A

Bordetella Bronchiseptica

*can lead to bronchopneumonia in many species

6
Q

What species of Bordetella causes Turkey Coryza?

A

Bordetella Avium

7
Q

What virulence factor does Bordetella express, but only in warm environments of around 37 degrees?

A

BvgAS- bordetella virulence gene

*avirulent at 25 degrees

8
Q

What kind of disease is associated with Bordetella?

A

respiratory

9
Q

Bordetella can cause _____

A

hemagglutination

10
Q

What important virulence factor of Bordetella helps with adherence to the respiratory tract?

A

Tracheal colonization factor

*This is only expressed by Bordetella Pertussis. Targets trachea. Not expressed in Bordetella Parapertussis or Bronchiseptica

11
Q

What outer membrane proteins does Bordetella have?

A

Pertactin and Brk (Bordetella resistance to killing)

12
Q

What siderphore is particular to Bordetella species?

A

Alcaligin

13
Q

What type of secretion system does Bordetella use?

A

Type III secretion system

14
Q

What are the 5 exotoxins important with Bordetella and what do they do?

A

Tracheal cytotoxin- toxic to cells within the trachea

Dermonecrotic toxin- destruction of turbinates in atrophic rhinitis

Adenylyl cyclase toxin- results in fluid loss

Pertussis Toxin- only active in B. pertussis and results in fluid loss

Osteotoxin- lethal to tracheal and bone cells

15
Q

How is Bordetella transmitted?

A

Direct Contact

*needs close contact

16
Q

Bordetella leads to depression of respiratory _____ and can lead to secondary ____ complications

A

depression of respiratory clearance

secondary pneumonia complications

17
Q

In pigs, nasal irritation associated with Bordetella can open the doors for _____ to infect

A

Pastuerella Multocida

18
Q

What is the medical term for kennel cough?

A

Canine infectious tracheobronchitis

19
Q

What other pathogens can co-infect with Kennel cough?

A

parainfluenza virus

adenovirus

canine herpesvirus

20
Q

Dogs with ____ are at a higher risk for develping pneumonia associated with Bordetella because they are immunosuppressed

A

distemper

21
Q

True/False: Coughing is common in cats with Kennel cough?

A

False

*couging is not common with cats

22
Q

Atrophic rhinitis is associated with what two bacteria?

A

Bordetella Bronchiseptica and Pasteurella Multocida

Note on image: KNOW THESE IMAGES. B and C show pig after infection when there has been erosion of nasal turbinates

23
Q

Atrophic rhinitis usually occurs in ____ pigs and _____ are carries that can spread the bacteria to their progeny and other progeny

A

occurs in young pigs

Sows are carriers

24
Q

True/False: Turkey Corya is highly infectious and causes high mortality

A

False

it is highly contagious in young turkeys but has a low mortility rate of less than 5%

25
Q

What does Turkey Coryza cause in the trachea?

A

tracheal degenration and flattening making it hard for the bird to breath

26
Q

If Bordetella comes into the mix with Snuffles (P. multocida) then it can cause _____ in rabbits

A

Bronchopneumonia

27
Q

Bordetella depresses the immune system by telling ____ cells not to secrete as much

A

dendritic cells

28
Q

Bordetella are strict ____

A

aerobes

*they are in the respiratory tract

29
Q

What is the best way to control Atrophic Rhinitis?

A

vaccines are available for pigs

CLEAN facility

*not treatable in advanced cases

30
Q

What is the best way to control Canine tracheobronchitis?

A

ventilation of kennels to keep the air moving

*vaccination doesn’t help much

31
Q

Is there a vaccine available for Turkey Coryza?

A

Yes