Blood Vessels Pathology Flashcards Preview

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Flashcards in Blood Vessels Pathology Deck (39)
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1
Q

[syndrome]

gain of function of ENaC channel resulting to increased Na reabsorption and then hypertension

A

Liddle Syndrome

2
Q

Associated condition

eosinophilic hyaline material with associated luminal narrowing

A

essential hpn

DM

3
Q

[associated condition]

concentric, laminated thickening, onion skin lesion, note of fibrinoid deposition and vessel wall necrosis

A

malignant hypertension

4
Q

location of neovascularization in an atheromatous plaque

A

periphery

5
Q

[clinical phase of atherosclerosis]

mural thrombosis, embolization, and wall thickening can lead to

A

aneurysm and rupture

6
Q

[clinical phase of atherosclerosis]

plaque rupture, plaque erosion, plaque hemorrhage, mural thrombosis, embolization can lead to

A

occlusion by thrombus

7
Q

[clinical phase of atherosclerosis]

progressive plaque growth can lead to

A

critical stenosis

usually 70%

8
Q

the larger the lipid core, the ____stability of the plaque

A

greater the stability of the plaque

Remember, size of lipid core is inversely proportional to stability

9
Q

the lesser the degree of inflammation, the ____ stability of the plaque

A

greater stability

remember, degree of inflammation is inversely proportional to stability

10
Q

the thicker the fibrous cap, the ___ stable the plaque

A

more stable the plaque

fibrous cap is directly proportional to stability

11
Q

[dissection]

intima tear involvinf the descending aorta only.

What is the standford classification?

A

Stanford B

DeBakey III = Standford B

12
Q

[aortic dissection]

Both ascending and descending aorta are involved.

What is it s debakey classification?

A

DeBakey I

13
Q

[diagnosis?]

45/M, hypertensive with marfan syndrome.

Noted sudden, excruciating anterior chest pain, radiating to the back and downward

A

aortic dissection

14
Q

[syndrome]

Non-infectious small artery vasculitides, p-anca positive

A

churg-strauss syndrome

15
Q

[syndrome]

non-infectious small artery vasculitides, c-anca positive

A

Wegener granulomatosis/ granulomatosis with polyangitis

16
Q

[diagnosis]

headache among elderly individual, along course of superficial temporal artery, associated with multiple joint pains

A

giant cell arteritis

17
Q

[diagnosis]

affects large vessels of the aortic arch, notable ocular disturbances and weakened UE pulses

A

takayasu

18
Q

[diagnosis]

associated with hepatitis B, renal and visceral vessels (NEVER PULMONARY)

clinically, HPN and visceral ischemia

prominent fibrinoid necrosis, segmental, transmural, necrotizing

A

polyarteritis nodosa

19
Q

[diagnosis]

fever >5 days, conjunctival injection, mucosal erythema, cervical lymphadenopathy, polyamorphous exanthem

A

kawasaki disease

20
Q

important cause of MI in children; can cause coronary artery aneurysm

less prominent fibrinoid necrosis, segmental, transmural, necrotizing

A

kawasaki disease

21
Q

[diagnosis]

associated with connective tissue disorders

common in kidney and LUNG; hemoptysis, hematuria

A

microscopic polyangitis

PAN = no lung involvement

22
Q

[diagnosis]

associated with asthma, allergic rhinitis, eosinophilia

noted involvement of cutaneous, GIT, renal and cardiac vessel

Clinically, palpable purpura, GI bleed and FSGS

A

churg-strauss syndrome

23
Q

[diagnosis]

PAN + extravascular necrotizing granulomas and hypereosinophilia

A

Churg-strauss syndrome

Remember, atopy/eosinophilia = sneeze = aaachooo = aaaachurg

24
Q

[diagnosis]

fragmented PMNs in post capillary venule (leukocytolasia)

A

Microscopic polyangitis

25
Q

[diagnosis]

prominent pulmonary involvement, may also involve renal vessels necrotizing granulomas of respiratory tract, necrotizing or granulomatous vasculitis, focal segmental necrotizing GN

c-ANCA positive

A

Wegener granulomatosis

26
Q

[diagnosis]

recurrent oral aphthous ulcers, genital ulcers, uveitis, neutrophilic infiltration of vessels

small to medium sized vessels are affected

A

Behcet syndrome

27
Q

[diagnosis]

strongly associated with cigarette smoking, small to medium vessel involvement, reynaud phenomenon, intermittent claudication, thrombosis with microabcesses

A

buerger disease

Thromboangitis obliterans

28
Q

most important risk factor for lower extremity DVT

A

prolonged immobilization

29
Q

[diagnosis]

migratory superficial vein thrombophlebitis in cancer patient

A

trosseau syndrome

30
Q

[diagnosis]

lower extremity edema, superficial abdominal vein distention, massive proteinuria (if renal vein is involved)

A

IVC syndrome

31
Q

most common cause of lymphangitis and lymphedema

A

GABHS

32
Q

[diagnosis]
facial port wine nevi, ipsilateral leptomeningeal cortical venous angiomas, mental retardation, seizures, hemiplegia, skull radioopacities

A

Struge-Weber syndrome

33
Q

[diagnosis]
AD defect in TGF beta
telangectasia on skin, oral mucosa, respiratory, GIT, urinary tract

A

Osler-weber-rendu disease

34
Q

[diagnosis]

rapidly growing, red, pedunculated lesion on the skin, gingival or oral mucosa

A

pyogenic granuloma

35
Q

cavernous lymphangiomas of the neck is more common in ___ syndrome

A

Turner

36
Q

[diagnosis]

african, <40 years old, HIV negative, HHV 8

A

Endemic Kaposi Sarcoma

37
Q

[diagnosis]

HHV 8 in HIV positive patients

A

epidemic kaposi sarcoma

38
Q

Thorotrast exposure is associated with this malignant tumor

A

hepatic angiosarcoma

39
Q

Stains used in angiosarcomas

A

CD31, CD34, vWF