Flashcards in Blood Banking Test 1: Chapters 11, 23, 25, 26 Deck (160)
What is the regulating agency for Blood Banking?
Food and Drug Administration
Blood Banking seeks accreditation from...
American Association of Blood Banks (AABB)
Definition: a facility involved in the collection, storage, processing, and distribution of human blood and blood products for transfusion
A blood bank laboratory
After collection, _____ ______ is allowed to cool to room temperature if ________ are to be prepared from the unit.
After collection, ______ ______ is cooled between 1C-10C if the unit is to be processed for ______ ______
What is the difference between FFP and FP24 regarding preparation?
FFP must be prepared within 8 hours of collection of the whole blood unit
FP24 may be prepared up to 24 hours following collection of the whole blood unit
What is the required temperature for storing blood products such as whole blood, RBCs, or thawed plasma, in a refrigerator?
1C to 6C
What is the required temperature for storing frozen plasma and cryo in freezers?
-18C or lower
What is the required temperature for storing frozen RBCs in freezers?
-65C or lower
What is the required temperature for platelet incubators?
20C - 24C
True or False:
Tests must be performed at each donation regardless of the number of times a donor has previously donated.
True or False:
Labeling of blood products occurs only after there have been no discrepancies in the ABO and Rh testing.
False, there should be no discrepancies in ABO and Rh testing as well as the absence of detectable antibodies in the plasma-containing components, nonreactive viral marker tests, and nonreactive syphilis test
When a blood bank receives a shipment what are they required to do to each RBC-containing product?
Reconfirm the labeled ABO
The Rh type of all Rh-_______ units must be reconfirmed when a shipment is received at a blood bank
A minimum of ___ identifiers is required for patient samples used for blood bank testing.
2 identifiers; The patient's full name and 1 other unique identifier
This type of routine testing allows better utilization of blood supplies; ABO and Rh testing and antibody screening are performed; the patient's transfusion record is checked; and if an antibody is detected the antibody is identified, and compatible units are reserved for the patient.
Type and Screen
This type of routine testing reserves completely tested and crossmatched blood for the patient
Type and Crossmatch
This type of routine testing includes determination of the ABO group and Rh type of the mother and antibody screen for antibodies that have the potential to cause HDFN
This type of routine testing requires that all women admitted for delivery be tested to determine their Rh status. If mom is Rh-negative and baby is Rh-positive, the maternal sample is further evaluated to detect a fetomaternal hemorrhage (FMH)
What 3 tests are used to test for FMH >30 mL whole blood?
Kleihauer-Betke Test, flow cytometry, or enzyme-linked antiglobulin test
What is required in order for blood components to be released to the designated recipient after pretransfusion testing is complete?
Written request with proper patient identification (2 unique identifiers)
What can an immune reaction to a drug, a disease state, or a delayed hemolytic transfusion reaction cause?
What may mask the presence of clinically significant alloantibodies and requires the removal of RBC-bound autoantibody followed by serum autoadsorption?
What may cause ABO discrepancies, a positive DAT, and may mask clinically significant alloantibodies?
What requires the removal of RBC-bound autoantibody using 37C saline?
These are manuals outlining the operations of the laboratory.
Standard Operating Procedures (SOPs)
These devices produce sterile welds between two pieces of compatible tubing.
Sterile connecting devices
This process renders donor lymphocytes nonfunctional and protects against graft-versus-host disease.
RBCs stored in freezers maintained at -65C or lower are frozen in what?