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Flashcards in Blood Deck (317)
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31

Give the plasma volume of the body

45 ml/bwkg

32

Give the blood cell volume of the body

35 ml/bwkg

33

Formula to calculate blood volume

V = Vrbc / 0.9 x Ht

V = Vp / (1-0.9 x Ht)

Vp = Plasma volume

Vrbc = blood cell volume

Ht = Hematocrit value

34

1, 4 and 7 are examples of...

Normocythaemia

35

2, 5 and 8 are examples of

Polycythaemia

36

3, 6 and 9 are examples of...

Olygocythaemia

37

Normocythaemic normovolaemia

Healthy blood volume

38

Polycythaemic normovolaemia

  • Haemoconcentration
  • Viscosity increases
  • Increased load on heart

39

Olygocythaemic normovolaemia

  • Haemodilution
  • Blood gets diluted with concurrent normal volume

40

Normocythaemic hypovolaemia (Oligaemia)

  • Blood cells and plasma loss together
  • Blood loss
  • Plasma replaced quickly
  • Cells return slowly

41

Polycythaemic hypovolaemia

  • Anhydraemia: Lack of water/thirst
  • Haemoconcentration

42

Normocythaemic hypervolaemia

  • Plethora (A large amount)
  • Excess transfusion
  • Permanent, exhausting physical work

43

Olygocythaemic hypervolaemia

  • Hydraemia
  • Intake of excess water
  • Infusion (followed by haemodilution)

44

Factors affecting blood volume

  • Body fat
  • Body position
  • Muscle work
  • Climate
  • Nutrition
  • Age
  • Pregnancy
  • Changes in water supply

45

Give the size of blood cells in:

  • Mammals
  • Birds

  • Mammals: 6x2 µm
  • Birds: 12x7 µm

46

Mean number of RBCs in the body

5 x 1012/L

47

Mitochondria are not present in RBCs, true or false

True

48

Average lifetime of RBCs

Average: 120 days

Cattle, swine: 60 days

Birds: 30 days

49

Haemoglobin concentration of blood

  • 120-180 g/l
  • 1.5-2.5 mmol/l

50

Haemoglobin content in 1g of RBCs

0.35g

35% haemoglobin concentraion

51

MCHC

Mean corpuscular hemoglobin concentration

Approx 5mmol/l

52

Calculate MCHC

Hb/Ht

Hb = Hemaglobin

Ht = Hematocrit

53

MCH

Value

Mean corpsucular hemoglobin

0.45 fmol/pc

54

Calculate MCH

Hb/RBC

55

MCV

Mean corpuscular volume

80-100 femtoliter/pc

56

Calculate MCV

Ht/RBC

57

Hemolysis

Leakage or disruption of the blood cells

Can be:

  • Hypoosmosis
  • Hyperosmosis

58

Hypoosmosis

  1. Blood cells placed in hypotonic solution
  2. Water flows into cells
  3. Cells swell and disrupt

59

Hyperosmosis

  1. Blood dropped into hypertonic solution
  2. Water leaves the cells
  3. Cells shrink

60

Osmotic resistance

RBCs adapt and are therefore resistant to the significant changes of osmotic circumstances