Blood 4: Blood Groups Flashcards Preview

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Flashcards in Blood 4: Blood Groups Deck (8)
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1

How blood group systems are there?

About 15
However ABO and rhesus are most commonly used

2

Natural occurring blood antibodies vs immune antibodies

Naturally occurring: Present in those never exposed to antigen eg. ABO antibodies
Immune: Occur following exposure to antigen eg. Rhesus D

3

What are the most common immune antibody groups?

Rhesus
Kell
Duffy

4

Describe ABO inheritance

pair of genes (one from each parent) form phenotype. Both genes expressed. 3 types of genes A, B or O (no antigen). Mendelian inheritance

5

What is the role of anti-D?

Prevent immune antibodies in someone who is rhesus negative exposed to rhesus antigen (eg in pregnancy)

6

How long can RBC be stored?

Several weeks with citrate-phosphate-dextrose solution

7

What are issues with RBC storage?

Gradual loss of ATP, and loss of cellular K=, can lead to increased serum K+ and decreased serum pH.

8

How long can platelets be stored?

48 hours