Flashcards in Blood 3: WBC Deck (9)
What are the 2 main groups of WBC?
- polymorphonuclear/ granulocytes
What are the 5 types of leukocytes identified on blood film?
Describe granulocyte production
Myeloblast formed from common progenitor cell -> promyelocyte -> myelocyte
Control of production depends on number of growth factors including GCSF
Neutrophilia is commonly secondary to what?
Bacterial infection, inflammation, necrosis or acute haemorrhage
What is the difference between active and passive immunity?
Active - antibodies produced by host
Passive - antibodies present from outside source - eg breast milk
What are the 2 groups of lymphocytes?
T cells and B cells
Where are T cells produced and what is there function
Originate in marrow, mature in thymus.
T helper - bind to antigen presenting cells and either aid cell mediated response or antibody production
T suppressor - dampen down immune resonse
T effector - Kill infected cells
What are cytokines are what are their functions?
Low molecular weight proteins that regulate cell immunity
1. Enhance inflammatory response
2. Induce growth and differentiation of immune cells
3. Influence predominance of either cell mediated or antibody mediated immune response
4. Establishing antiviral activity (interferon is a cytokine)