BL - Immunohemotology ABO/Rh Flashcards
Red cells do not carry _____ in humans, and the antigens they do carry are much less polymorphic in the population (that is, many fewer alleles).
MHC antigens
When people repeatedly need ____, which do bear HLA (Class I), they may develop an alloimmunization problem, in which case HLA typing as well becomes necessary.
platelets
_____ are glycolipids found on the surface of all body cells.
Blood group antigens
The ____ spans the plasma membrane, and the terminal sugars confer the antigenic specificity (A, B, or O).
lipid backbone
A set of _____ assemble the basic “core” sugar chain which almost everybody has, called the “H” antigen.
glycosyl transferases
A final glycosyl transferase adds one of three alleles: ____.
A, B, or AB
Type O blood only has the _____ and no working transferase.
basic core H antigen
Red cells do not carry MHC antigens in humans, and the antigens they do carry are much less ____ in the population (that is, many fewer alleles).
polymorphic
Blood group antigens are _____ found on the surface of all body cells.
glycolipids
When people repeatedly need platelets, which do bear HLA (Class I), they may develop an ______ problem, in which case HLA typing as well becomes necessary.
alloimmunization
The lipid backbone spans the plasma membrane, and the ____ confer the antigenic specificity (A, B, or O).
terminal sugars
A set of glycosyl transferases assemble the basic “core” sugar chain which almost everybody has, called the _____.
H antigen
____ only has the basic core H antigen and no working transferase.
Type O blood
_____ blood have a glycosyl transferase allele which puts an additional different sugar on the H antigen.
Group A and B
What is the Bombay phenotype?
blood type without the H antigen, so all other blood including O is foreign
