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Flashcards in Bipolar/Psychosis Deck (47)
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1

Which drug is the most effective long term therapy for bipolar, protection against depression + mania, and decreases risk of suicide/short term mortality?

Lithium

2

When dosing lithium, what should you do?

Start low and titrate up, then monitor the patient's levels

3

What are some things we must monitor when a patient is on lithium?

Pregnancy test Renal fxn Thyroid fxn Weight

4

Your patient is going to begin lithium for their bipolar diagnosis. What ADRs must you tell them about?

GI issues, nausea, fatigue

Tremor

Weight gain

Polyuria/polydipsia

Hypothyroidism

5

Why is it important to do a pregnancy test for a patient on lithium?

Teratogenic Associated with Ebstein's anomaly

6

Chlorpromazine and Thioridazine are what type of drugs?

1st gen anti-psychotics (low potency)

7

Which 1st gen anti-psychotic is good for treating intractable hiccups?

Chlorpromazine

8

Haloperidol is what type of drug?

1st gen anti-psychotic

9

Which 1st gen anti-psychotic would help for emergency sedation of a severely agitated or delirious patient?

Haloperidol

10

What class is perphenazine in?

1st gen anti-psychotic

11

What class is fluphenazine in?

1st gen anti-psychotic

12

What class is loxapine in?

1st gen anti-psychotic

13

What class is molindone in?

1st gen anti-psychotic

14

What class is thiothixene in?

1st gen anti-psychotic

15

What class is trifluoperazine in?

1st gen anti-psychotic

16

What are the major ADRs associated with 1st gen anti-psychotics?

EPS - tardive dyskinesia

NMS

Postural hypotension

Sedation

QTc prolongation

Increased prolactin

17

What is beneficial for 2nd gen anti-psychotics in comparison to 1st gen anti-psychotics?

Less risk of EPS

18

Which 2nd gen anti-psychotic is the most effective and used for refractory schizophrenia?

Clozapine

19

What class is risperidone in?

Atypical Anti-psychotics (2nd gen)

20

What class is olanzapine in?

Atypical Anti-psychotics (2nd gen)

21

What class is quetiapine in?

Atypical Anti-psychotics (2nd gen)

22

What class is ziprasidone in?

Atypical Anti-psychotics (2nd gen)

23

What class is paliperidone in?

Atypical Anti-psychotics (2nd gen)

24

What class is asenapine in?

Atypical Anti-psychotics (2nd gen)

25

What class is Iloperidone in?

Atypical Anti-psychotics (2nd gen)

26

What class is lurasidone in?

Atypical Anti-psychotics (2nd gen)

27

What class is cariprazine in?

Atypical Anti-psychotics (2nd gen)

28

What class is brexpiprazole in?

Atypical Anti-psychotics (2nd gen)

29

What class is aripiprazole in?

Atypical Anti-psychotics (2nd gen)

30

Black box warning for Atypical Anti-psychotics (2nd gen)

Increased mortality risk in dementia-related psychosis and suicidality for depression