Flashcards in Biochemistry Deck (372)
What does the G of HGPRT stand for? (Mnemonic)
What is allopurinol an analogue of?
What rxn is catalyzed by amidophosphoribosyltransferase? What amino acid is consumed and a byproduct? What metabolic pathway is this enzyme involved in the committed step of?
PRPP to PRA
Gln to Glu
What type of prokaryotic topoisomerases do fluoroquinolones inhibit?
What six nucleotide fragment does telomerase add? What end of the DNA?
Does telomerase use an RNA or DNA primer?
What type of muscular dystrophy features a frameshift mutation?
Is the triphosphate on the 5' or the 3' end of the incoming nucleotide?
What is the function of the CCA of tRNA?
transport amino acids
What is the function of rRNA?
catalyze peptide chain growth
What Cyclin corresponds to G0? Which CDK?
Which cyclin corresponds to G1? Which CDK?
D and E
2, 4 and 6
Which cyclin corresponds to S? Which CDK?
A and E
Which cyclin corresponds to G2? Whick CDKs?
2 and 1
Which cyclin corresponds to M? Which CDKs?
What is the function of Nissl Bodies?
site of neurotransmitter synthesis
Rather than being trafficked to lysosomes, what happens for proteins in I-cell disease?
What type of collagen is reticulin found in?
What are the three main manifestations of Alport Syndrome?
3. bilateral hearing loss
What three tissues is Type IV collagen most important?
kidney, ear and eye
What two tissues are most effected by Goodpasture Syndrome?
lungs and kidneys
Lysyl oxidase forms cross linkages between which two amino acid residues of collagen?
lysine and hydroxylysine
What veins are visible in the eye during Osteogenesis Imperfecta?
What normal component of teeth can be absent during Osteogenesis Imperfecta?
What two types of aneurysms can be present in Ehlers-Danlos Syndrome?
berry and aortic
What type of collagen is most most commonly effected during Ehlers-Danlos Syndrome?
What enzyme is primarily effected during Menkes Disease? Leading to a deficiency of?
What type of degeneration can occur in the CV system due to Marfans?
cystic medial degeneration
Fibrillin-1 sequesters what cytokine?