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Flashcards in Biochemistry Deck (372)
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211

What does the G of HGPRT stand for? (Mnemonic)

gour

212

What is allopurinol an analogue of?

Hypoxanthine

213

What rxn is catalyzed by amidophosphoribosyltransferase? What amino acid is consumed and a byproduct? What metabolic pathway is this enzyme involved in the committed step of?

PRPP to PRA

Gln to Glu

Purine

214

What type of prokaryotic topoisomerases do fluoroquinolones inhibit?

Type II

215

What six nucleotide fragment does telomerase add? What end of the DNA?

1. TTAGGG

2. 3'

216

Does telomerase use an RNA or DNA primer?

RNA

217

What type of muscular dystrophy features a frameshift mutation?

Duchenne

218

Is the triphosphate on the 5' or the 3' end of the incoming nucleotide?

5'

219

What is the function of the CCA of tRNA?

transport amino acids

220

What is the function of rRNA?

catalyze peptide chain growth

221

What Cyclin corresponds to G0? Which CDK?

C

CDK3

222

Which cyclin corresponds to G1? Which CDK?

D and E

2, 4 and 6

223

Which cyclin corresponds to S? Which CDK?

A and E

2

224

Which cyclin corresponds to G2? Whick CDKs?

A

2 and 1

225

Which cyclin corresponds to M? Which CDKs?

B

1

226

What is the function of Nissl Bodies?

site of neurotransmitter synthesis

227

Rather than being trafficked to lysosomes, what happens for proteins in I-cell disease?

secreted extracellularly

228

What type of collagen is reticulin found in?

Type III

229

What are the three main manifestations of Alport Syndrome?

1. hematuria

2. proteinuria

3. bilateral hearing loss

230

What three tissues is Type IV collagen most important?

kidney, ear and eye

231

What two tissues are most effected by Goodpasture Syndrome?

lungs and kidneys

232

Lysyl oxidase forms cross linkages between which two amino acid residues of collagen?

lysine and hydroxylysine

233

What veins are visible in the eye during Osteogenesis Imperfecta?

choroidal veins

234

What normal component of teeth can be absent during Osteogenesis Imperfecta?

dentin

235

What two types of aneurysms can be present in Ehlers-Danlos Syndrome?

berry and aortic

236

What type of collagen is most most commonly effected during Ehlers-Danlos Syndrome?

Type V

237

What enzyme is primarily effected during Menkes Disease? Leading to a deficiency of?

lysyl oxidase

collagen

238

What type of degeneration can occur in the CV system due to Marfans?

cystic medial degeneration

239

Fibrillin-1 sequesters what cytokine?

TGF-β

240

What is imprinted in Prader-Willi? Deleted?

mother = imprinted

father = deleted