Flashcards in Biochemistry Deck (372)
What kind of pregnancy is more common in Kartagener syndrome?
What is the sterol of fungal cell walls?
Vimentin is an immunohistochemical marker of what tissue type?
Desmin is an immunohistochemical marker of what tissue type?
Cytokeratin is an immunohistochemical marker of what tissue type?
GFAP is an immunohistochemical marker of what tissue type?
Oubain inhibits what transporter?
Where on the Na+/K+ ATPase does Oubain bind?
K+ binding site
What are three tissues where Type I collagen is found?
bone, tendon, skin
Where is type two cartilage found?
What type of collagen is found in blood vessels?
What type of collagen is targeted in Alport syndrome?
What type of collagen is targeted in Goodpasture syndrome?
Collagen is composed of 1/3 of what amino acid?
What do X and Y of Gly-X-Y stand for?
proline and lysine
What type of post-translational modification occurs to collagen other than hydroxylation? At what residues?
Problems forming the triple helix of collagen result in what disease?
What is cleaved to form tropocollagen from procollagen?
disulfide rich regions
What enzyme forms cross-links in tropocollagen? What is required as a co-factor?
What disease results if lysyl oxidase is defective?
The most common form of osteogenesis imperfecta is caused by what defects in what type of collagen?
Where does a berry aneurysm occur? What disease predisposes one to a berry aneurysm?
cerebral artery bifurcating from CoW
What is not absorbed in Menkes Disease? What are two characteristics of the most common manifestation of Menkes Disease?
brittle and kinky hair
Elastin is rich in which two amino acids? Hydroxyated or non-hydroxylated?
proline and glycine
What inhibits elastase?
Marfan syndrome is characterized by a defect in what protein? What is the purpose of this protein?
What cytokine cannot bind fibrillin in Marfan syndrome? What two body parts can result in a fatality in marfan syndrome?
aorta and heart valves
What is the mnenomic for remembering what southern, northern and western blots look for?
An indirect ELISA uses what as a probe? What is being looked for?
indirect = antigen
looking for antibody