Flashcards in Basic CNS Biochemistry Deck (16)
Neurotransmitters can be divided into broad groups, what are they?
Small molecule neurotransmitters (tend to be fast acting)
Neuropeptides (tend to be slow acting)
Small molecule neurotransmitters tend to be packaged in what kind of vesicles?
Small clear vesicles
Neuropeptides tend to be packaged in what kind of vesicles?
Large dense core vesicles
What is "co-transmission"?
Neurotrons releasing more than one neurotransmitter
Botulinum toxin inhibits which protein to prevent pre-synaptic NT release?
What are the two broad classes of NT receptor?
Which enzyme synthesises Acetylcholine? What are the substrates?
(Choline + Acetyl-CoA)
What are the subtypes for the Muscarinic Acetylcholine Receptor?
M1 M2 M3 M4 M5
What are the three Glutamate receptors?
What is the mechanism of action for Donepezil?
What is the precursor for GABA?
How is Dopamine synthesised?
Tyrosine --- L-DOPA ----- Dopamine
The clinical features of Parkinsons is TRAP. What is TRAP?
What is the precursor for Noradrenaline?
How is 5-HT degraded?