Barbiturates Flashcards Preview

ANPH 500 - Pharmacology - McCarver > Barbiturates > Flashcards

Flashcards in Barbiturates Deck (10)
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What is a barbiturate?

Any drug derived from barbituric acid.

1

Why have barbiturates fallen out of favor?

the "hangover" effect that results in prolonged drowsiness.

2

Barbiturates are _ salts and are soluble in _ and form highly _ solutions.

sodium
water
alkaline

PH of pentathol is 10-11

3

Barbiturates are incompatible with what drugs?

Opioids
NMBs
Catecholamines

4

Barbiturates are available on as what type of mixture?

Racemic

5

Barbiturates are levorotary isomers of __ and __ and are twice as potent as __.

Thiopental
Thiamylal
dextrorotary isomers

6

Barbiturates are only available as what concentration of solutions?

2.5% (5% is to caustic to vessels!)

7

Prompt awakening from SINGLE dose barbiturates is from what?

REDISTRIBUTION

8

Barbiturates have __ CNS activity, and are formed from uria and __ acid.

NO (weird right?)
malonic

9

Substitution at # 2 & #5 ___ help determine drug ___.

carbons
characteristics