Barbiturates Flashcards Preview

ANPH 500 - Pharmacology - McCarver > Barbiturates > Flashcards

Flashcards in Barbiturates Deck (10)
Loading flashcards...
0
Q

Why have barbiturates fallen out of favor?

A

the “hangover” effect that results in prolonged drowsiness.

1
Q

What is a barbiturate?

A

Any drug derived from barbituric acid.

2
Q

Barbiturates are _ salts and are soluble in _ and form highly _ solutions.

A

sodium
water
alkaline

PH of pentathol is 10-11

3
Q

Barbiturates are incompatible with what drugs?

A

Opioids
NMBs
Catecholamines

4
Q

Barbiturates are available on as what type of mixture?

A

Racemic

5
Q

Barbiturates are levorotary isomers of __ and __ and are twice as potent as __.

A

Thiopental
Thiamylal
dextrorotary isomers

6
Q

Barbiturates are only available as what concentration of solutions?

A

2.5% (5% is to caustic to vessels!)

7
Q

Prompt awakening from SINGLE dose barbiturates is from what?

A

REDISTRIBUTION

8
Q

Barbiturates have __ CNS activity, and are formed from uria and __ acid.

A

NO (weird right?)

malonic

9
Q

Substitution at # 2 & #5 ___ help determine drug ___.

A

carbons

characteristics