Autoimmune Dx - Overview Flashcards Preview

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Flashcards in Autoimmune Dx - Overview Deck (9)
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0
Q

List autoimmune dx

A
Rheumatoid arthritis (RA)
Systemic lupus erythematous (SLS)
Multiple sclerosis (MS)
Celiac dx
Sjögren's syndrome 
Type I diabetes 
Hashimoto's thyroiditis
Graves dx
1
Q

What’s autoimmune dx?

A

Illnesses that occur when the body’s tissues are attacked by the person’s own immune system

2
Q

List the conditions that can make a pt immunocompromised.

A

Dx states which destroy key components of the immune response eg HIV

Steroids (oral or injectable) taken > 14 days (at dose of 2mg/kg/day or 20 mg prednisone or prednisone-equivalent dose)

Oncology tx that destroys white blood cells

Transplant drugs that depress immune system

Asplenia (lack of functioning spleen)

3
Q

List labs that may be associated with autoimmune dx

A

C-reactive protein (CRP)

Erythrocyte sedimentation rate (ESR)

Rheumatoid factor (RF)

Anti-nuclear antibodies (ANA)

4
Q

What’s the role of the autoimmune drugs?

A

They dampen the immune response

5
Q

What conditions tend to increase with the use of immune responses?

A

TB and hepatitis B

Virus; if viruses can be prevented by a live vaccine, the vaccine must be given prior to the start of tx

Lymphoma and certain skin cancers (these cancers are normally suppressed by the immune system)

Infections of various types

6
Q

If live vaccines are needed, when should they be given?

A

Prior to the start of Immunosuppresive drugs

7
Q

List live vaccines that may be needed?

A

Measles

Rubella

Varicella

Zoster

Yellow fever

8
Q

List the inactivated vaccines needed by immunocompromised pts

A

Influenza vaccine (inactivated)

Tdap

Pneumococcal

HPV vaccine for men and women up to the age of 26yrs

Meningococcal vaccine (either MPSV4 or MC4) for pts with a damaged spleen or terminal complement deficiency

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