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Nurs 5229 Clinical Pharmacotherapeutics > anticoagulation overview > Flashcards

Flashcards in anticoagulation overview Deck (8)
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1
Q

Substances that promote coagulation:

A

◦ Platelets
◦ Activated clotting factors
◦ Von Willebrand factor ◦ Tissue thromboplastin
◦ Factor V Leiden

2
Q

Substances that inhibit coagulation

A

◦ Prostacyclin
◦ Antithrombin II and III
◦ Proteins C and S

3
Q

Vichow’s Triad

A

2 of 3 risk factors must be present for clot to form

◦ Venous stasis risk
◦ Damage to venous epithelium
◦ Hypercoagulable state

4
Q

Other risk factors: for clotting

A

> 40 years, cigarette smoking, CV disease (a-fib, MI, HTN, CVA), DM, Joint arthoplasty, varicose veins or prior hx of thrombophlebitis, sepsis, trauma or spinal cord injury

5
Q

consequences of a clot

A

◦ DVT (deep vein thrombus) ◦ PE (pulmonary embolism) ◦ MI (myocardial infarction) ◦ CVA (cerebral vascular accident)

6
Q

oral anticoagulants

A

◦ Warfarin

◦ Factor Xa inhibitors

7
Q

Parenteral anticoagulants

A

◦ Heparin
◦ LMW Heparin
◦ Fondaparinux (Arixta)

8
Q

other types of drugs that work on clots

A

Antiplatelets

Thrombolytics