Antiarrythmics 4 (Amiodarone monitoring) Flashcards Preview

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Flashcards in Antiarrythmics 4 (Amiodarone monitoring) Deck (12)
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1

Monitoring for which side effect of amiodarone?

1. CXR (baseline, and then every 12 months)

2. PFTs (baseline and then if sxs develop)

3. high resolution CT (if sxs develop)

Pulmonary fibrosis

2

How should you manage Pulmonary fibrosis (SE of amiodarone)

 

-Discontinue amiodarone immediately

-may consider corticosteroid therapy

3

what is the monitoring recommendation for hyper and hypothyroidism, a side effect of amiodarone

 TFTs (baseline, and then every 6 months)

 

4

what is the management recommendation for hypothyroidism, a side effect of amiodarone

thyroid hormone supplementation (ex: levothyroxine)

5

what is the management recommendation for hyperthyroidism, a side effect of amiodarone

Antithyroid drugs (ex: methimazol, propylthiouracil) or corticosteroids

may need to discontinue amiodarone

6

what is the monitoring recommendation and management for optic neuritis/neuropathy, a side effect of amiodarone

monitoring: opthalmologic exam 

Management: discontinue amiodarone immedietly

7

what is the monitoring recommendation and management for corneal microdeposits, a side effect of amiodarone

monitoring: slit lamp exam  (routine monitoring not necessary)

management: no tx necessary

8

what is the monitoring recommendation and management for hepatotoxicity, a side effect of amiodarone

monitoring: LFTS

management: lower dose or discontinue if LFTs >2x upper limit of nml

9

what is the monitoring recommendation and management for Bradycardia/heart block, a side effect of amiodarone

Monitor: ECG (baseline, then Q3-6mo)

management: lower dose or discontinue if severe (or continue amiodarone and implant permanent pacemaker)

10

Which 2 side effects of amiodarone are monitored with history and physical exam each office visit

Tremor, ataxia, peripheral neuropathy, photosensitivity/blue-gray skin discoloration

11

What is the reccomended management of tremor, ataxia, peripheral neuropathy, side effects of amiodarone?

lower dose, or discontinue amiodarone if severe

12

What is the reccomended management of photosensitivity/blue-gray skin discoloration; side effects of amiodarone?

lower the dose; advise patients to wear sunblock outside