Wt gain if BMI < 19.8
Wt gain if BMI 20-26 normal
Wt gain if BMI 26-29 overweight
second trimester screening primarily detects what abnormalities
trisomy 18, 21 and neural tube defects
Wt gain if BMI >29 obese
Who needs complete genetic evaluation?
>35, personal hx, prev hx, family hx, abnormal screening
What produces AFP
yolk sac then fetal liver
why is AFP elevated in maternal blood 7 reasons
"leaking" from neural tube defect ventral wall defect Oligo renal abnormalities Ectopic inaccurate EGA Malpositioned placenta
AFP levels are dependent on what maternal characteristics? 5
Gestational Age Race Maternal Age Weight Diabetes
AFP results > 2.5 MOM can indicate?
Neural tube defect omphalocele anencephaly
What MOM is used for AFP in diabetic mom?
Decreased AFP can indicate...
What are the 4 markers in a Quad Screen?
AFP Uncongugated Estriol hCG DIA (dimetric inhibin A)
Quad markers for Trisomy 21
Quad markers for Trisomy 18
Preferred method of estimated gest age for AFP
BPD by sono
Gest age for AFP/Quad screen
#1 Reason for abnormal multiple marker screen?
error in EGA
Clinical follow up to an abnormal AFP/Quad screen?
Ultrasound Possible Amnio if US technology poor
Gest age for amnio?
Presence of what in amniotic fluid indicates a minimal risk of RDS in the newborn?
PG even when L/S is <2
The number of live births per 1000 population
The complete expulsion or extraction from the mother of a fetus after 20 weeks gestation or weighing 500gms or more.
the number of live births per 1000 females aged 15-44
the term used to record a birth whenever the newborn at or sometime after birth breathes spontaneously or shows any other sign of life such as a heartbeat or definite spontaneous movements of voluntary muscles
Stillbirth (fetal death)
the absence of signs of life at or after birth
Early – death of a liveborn neonate during the first 7 days after birth Late – death after 7 days but before 29days
All deaths of liveborn infants from birth to 12 months
A fetus or embryo removed or expelled from the uterus during the first half of gestation – 20 weeks or less / less than 500gms
Maternal mortality ratio
The number of maternal deaths that result from the reproductive process, per 100,000 live births. (known also as maternal mortality rate or maternal death rate)