Flashcards in Anemia/Blood parasites/WBC abnormalities Deck (217)
What is anemia?
decreased RBC count, hemoglobin concentration, and PCV
Anemia is a reduction of?
oxygen carrying capacity of the blood
Anemia is more commonly a result of a _____ disease process rather than a ____ disease.
T/F Once anemia has been detected, its cause should be investigated to determine the proper therapeutic management of the patient.
T/F Treatment is not to be directed at the anemia necessarily (unless it is an emergency) but the underlying cause which must be determined and corrected.
The development of clinical signs of anemia and their severity depends on what four things?
how rapid of an onset of the anemia, degree, cause, and physical activity of animal
T/F Relative anemia is the most common form.
Classification of relative and absolute(indices) anemia are based on what 3 factors?
1) erythrocyte morphology(regenerative or not)
2) indicies (MCV/MCHC)
3) bone marrow response
Morphology classification is based on the erythrocyte indices ___ and ___ .
When this classification is used a normal MCV is termed ____, a normal MCHC is _____
Evidence of bone marrow response to anemia is then obtained by determining the degree of _______ in the blood
Based on the bone marrow erythropoietic response evident in the peripheral blood, anemia is classified as ____ or ____.
regenerative or nonregenerative
How long does it take the bone marrow to show a positive response to blood loss?
What is regenerative anemia?
evidence of increased RBC production in the peripheral blood and bone marrow, must see an increased number of reticulocytes(polychromataphils)
In regenerative anemia what 5 things can you see a combination of?
1) reticulocytes 2) anisocytosis 3) polychromataphils 4) nRBCs 5) howell-jolly bodies-nuclear remanant
What is nonregenerative anemia?
when bone marrow is not responding, suggests that the primary cause of anemia has a pathologic or suppressant effect on the bone marrow
An expression of the percentage of RBCs that are reticulocytes
What is the best semiquantitative indicator of bone marrow response?
What 2 types of reticulocytes are seen in cats and should be counted?
punctate and aggregate
The absence of reticulocytes in an anemic patient suggests?
bone marrow failure, reduced erythropoietin production, or defective iron utilization
To incubate blood for a reticulocyte count of many drops of blood do you need? Stain? How long does it take?
3 drops of blood, 3 drops of stain, 10 minutes
T/F A corrected reticulocyte count above 1% in a dog and cat indicates an active response.
Regenerative anemia can cause what diease?
One third of the blood volume has been lost in a short period of time, shock occurs and death may ensue-tachycardia dyspnea
acute blood loss
What are the 4 signs of acute hemolytic anemia?
1)icterus/bilirubin 2)hemoglobemia 3)hemoglobiuria 4) fever
A PCV greater than 70% would suggest a primary?
What is relative polycythemia?
What is primary polycythemia?
If there is an increase in spherocytes what does that indicate?
immune mediated anemia