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Flashcards in Anemia Deck (78)
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1

Typical Symptoms of Anemia

shortness of breath, fatigue, rapid heart rate, dizziness, pain with exercise, pallor

2

Typical Signs of Anemia

tachycardia, tachypnea, dyspnea, and pallor

3

_____ detects ability of patient’s serum to bind IgG and/or complement to test normal RBCs

IAT

4

_____ evaluates presence of IgG or C3d or C4d on surface of patient cells by addition of Coomb's reagent.

DAT

5

_____ is synthesized by bacteria and algae, obtained by humans up the ladder through meat, eggs, and milk.

B12

6

________ in the stomach is bound by Intrinsic Factor (IF), which is secreted by gastric parietal cells

B12

7

An abnormal osmotic fragility test is characteristic of ________.

hereditary spherocytosis

8

Autimmune Hemolytic Anemia is evaluated for using the ______.

Direct Antiglobin Test (DAT)

9

B12 in the stomach is bound by ________, which is secreted by gastric parietal cells

Intrinsic Factor (IF)

10

B12 is absorbed and released from IF in the ________

terminal ileum

11

During iron deficient erythropoiesis, there is _____ in erythrocytes.

no change

12

During iron deficient, erythropoiesis, there is a ______ in iron binding capacity and a _______ in sautration of transferrin

increase; decrease

13

Enteroherpatic recirculation is characteristic of _____ (B12/folate)

folate

14

Fava beans are frequently associated with _____.

G6PD deficiency

15

Folate is absorbed in the _____.

jejunum

16

For a positive DAT, ____ AIHA is characterized by complement only and no IgG

Cold

17

For a positive DAT, ____ AIHA is characterized by strong IgG and weak complement.

Warm

18

Goat's milk is deficient in _____.

folate

19

Hepcidin binds to _____ to induce its degradation

Ferroportin

20

Hereditary spherocytosis occurs from defects in cytoskeletal proteins, especially: ______(3)

spectrin, ankyrin, band 3

21

In anemia related to endocrinopathies, RBCs are ____chromic and ____cytic

normo; normo

22

In B12 deficiency and folate deficiency anemias, plasma homocysteine is _____.

decreased

23

In B12 deficiency anemia, serum cobalamin is _____.

decreased

24

In B12 deficiency, RBCs are ____cytic.

macro

25

In chronic infection or inflammation, _____ diminishes iron mobilization and ____ production

IL-1; EPO

26

In folate deficiency, RBCs are ____cytic.

macro

27

In hemolytic anemia, reticulocyte count is _____

increased

28

In hemolytic anemia, serum haptoglobin is ____

decreased

29

In hemolytic anemias, bilirubin, LDH, and SGOT are ______

increased

30

In hereditary spherocytosis, MCV is _____

decreased