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Flashcards in Anemia Deck (17)
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1

Microcytic Anemia Iron deficiency-Eti & Patho

Most common anemia- due to deficiency, blood loss, decreased absorption, menstruation & pregnancy. Decrease in iron

2

Microcytic Anemia Iron deficiency- Sx

Pica-craving for ice chips, lettuce
Skin & mucosal changes- smooth tongue, brittle nails, spooning.
Easy fatiguability, tachycardia, palpitations, tachypnea

3

Microcytic Anemia Iron deficiency- Dx

CBC indicating low MCV & MCH, low serum ferritin values, therapeutic response to iron replacement

4

Microcytic Anemia Iron deficiency- Tx

Ferrous sulfate, treat underlying causes

5

Thalassemia- Eti

Hereditary disorder- reduction of hemoglobin synthesis. SE Asia & China, mediterranean

6

Thalassemia-

Signs & sx of anemia +, genetic risk factors
Minor- microcytic anemia
Major- growth failure, bony deformities, hepatosplenomegaly, jaundice

7

Thalassemia- Dx

Minor- Mild hematocrit deficiency, RBC, normal to increased, Mildly abnormal blood smear.
Major- Severe decrease in hematocrit, bizarre peripheral blood smear

8

Thalassemia- Tx

Minor- no tx, DO NOT give iron
Major- Folic acid & transfusion

9

Folic acid deficiency- Eti

Commonly due to inadequate dietary intake- alcoholics, anorexic, nutrition deficit, pregnancy

10

Folic acid deficiency- Sx

Glossitis, GI disturbances

11

Folic acid deficiency- Dx

Megaloblastic anemia with normal Vitamin B 12, low folate level

12

Folic acid deficiency- Tx

Folic acid supplement

13

Anemia of chronic disease- Eti

Elderly, organ failure, inflammation, cancer- often due to reduction of or resistance to erythropoietin and iron sequestration.

14

Anemia of chronic disease- Sx

Normocytic anemia- low hct, iron, high ferritin

15

Anemia of chronic disease- Tx

Treat primary cause of anemia

16

Intrinsic anemia

Caused by hereditary defects- affects components of RBC. Sickle cell, G6PD. paroxysmal nocturnal hemoglobinuria

17

Extrinsic anemia

Caused by destruction of RBC due to infection, meds, leukemia or lymphoma. RBCs are healthy when produced and destroyed by body.