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Flashcards in $$ AED Categories $$ Deck (30)
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1

"Old" 1st Gen AED

- phenobarbital
- phenytoin
- carbamazepine
- valproate
- ethosuximide

2

"New" 2nd Gen AED

- gabapentin
- pregabalin
- levetiracetam/brivaracetam
- lamotrigine
- oxcarbazepine/eslicarbazepine
- tiagabine
- topiramate
- zonisamide
- felbamate
- lacosamide
- rufinamide
- ezogabine
- vigabatrin
- perampanel
- BZDs (clobazam/clonazepam)
- cannabidiol

3

Partial, including secondarily generalized seizures

Carbamazepine
Lamotrigine
Levetiracetam
Oxcarbazepine

4

Primary generalized tonic-clonic seizures

Lamotrigine
Levetiracetam
Valproate

5

Absence Seizures

Ethosuximide
Valproate

6

Atypical Absence, Myoclonic, Atonic Seizures

Lamotrigine
Levetiracetam
Valproate

7

Drugs that affect Na channels

- carbamazepine
- oxcarbazepine/eslicarbazepine
- phenytoin/fosphenytoin
- lamotrigine
- lacosamide
- zonisamide
- rufinamide

8

Drugs that affect K channels

- ezogabine

9

Drugs that affect Ca2+ channels

- ethosuximide
- gabapentin
- pregabalin

10

Drugs that affect GABA activity

- phenobarbital
- clobazam
- clonazepam
- tiagabine
- vigabatrin

11

Glutamate Receptor Antagonists

- perampanel

12

Drugs w/multiple mechanisms of action

- valproate
- topiramate

13

Drugs w/unknown mechanism of action

- felbamate
- levetiracetam
- brivaracetam
- cannabidiol

14

AED that make absence or myoclonic seizures worse

1. carbamazepine
2. oxcarbazepine / eslicarbazepine
3. gabapentin

15

AED for LGS

1. lamotrigine
2. rufinamide
3. clobazam
4. clonazepam
5. felbamate
6. cannabidiol
7. topiramate

16

AED requiring ECG rhythm monitoring

1. IV phenytoin / fosphenytoin
2. lacosamide
3. rufinamide
4. ezogabine

17

AED and bicarb monitoring and oligohidrosis

1. zonisamide
2. topiramate

18

AED associated with euphoria; scheduled list

1. lacosamide
2. ezogabine
3. pregabalin
4. perampanel
5. brivaracetam
6. cannabidiol
7. BZDs

19

AED Teratogens

** VPA **

Other:
- topiramate
- phenytoin
- carbamazepine
- lamotrigine
- phenobarbital

20

AED with psychiatric concerns

1. levetiracetam
2. brivaracetam
3. ethosuximide
4. perampanel (homicide)
5. ezogabine

21

AED associated with SJS

1. carbamazepine
2. lamotrigine
3. zonisamide
4. Phenytoin

22

AEDs indicated for Post herpetic neuralgia or Trigeminal neuralgia

1. carbamazepine (trigeminal neuralgia)
2. gabapentin
3. pregabalin

23

AEDs indicated for manic/bipolar

1. carbamazepine
2. oxcarbazepine / eslicarbazepine
3. lamotrigine
4. valproate

24

AEDs indicated for Restless leg syndrome

1. gabapentin
2. pregabalin

25

AEDs that do autoinduction; must monitor concentration levels

1. carbamazepine
2. phenytoin / fosphenytoin
3. phenobarbital

26

AEDs causing SIADH (hyponatremia)

1. carbamazepine
2. oxcarbazepine / eslicarbazepine

27

AED causing retinal toxicity

vigabatrin

28

AEDs w/concern for hepatotoxicity

1. valproate*
2. phenytoin / fosphenytoin

29

AEDs indicated for migraine prophylaxis

1. valproate (cat X if pregnant)
2. topiramate

30

AEDs used for prevention of early seizures following TBI/NS

1. levetiracetam
2. phenytoin