ADRENERGICS HIGH YIELD Flashcards Preview

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Flashcards in ADRENERGICS HIGH YIELD Deck (15)
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1
Q

the nervous system is comprised of what two systems?

A
CNS
-brain
-spinal cord
PNS
-somatic NS
-autonomic NS
2
Q

what are the two division of the autonomic nervous system?

A

sympathetic (thoracolumbar)

parasympathetic (craniosacral)

3
Q

the primary NT of the sympathetic nervous system is _____?

A

norepinephrine

4
Q

this NT is released by the adrenal medial and acts as a hormone?

A

epinephrine

5
Q

the drugs that mimic the actions of EPI and NE are called?

A

sympathomimetic

6
Q

this the immediate precursor to NE?

A

dopamine

7
Q

what are the endogenous catecholamines?

A

dopamine
NE
Epi

8
Q

this AA is converted to _____, then to _____ which is converted to _____; this is then converted to _____?

A
tyrosine
dopa
dopamine
NE
epi
9
Q

effects of epi, NE, DA are mediated by?

A

G protein coupled receptor
a1-a2
b1-b3
d1-d2

10
Q

what are examples of the autonomic responses?

A
pupils dilate
HR increases
RR increases
Bronchi dilate
Muscles tense
Digestion slows
Salivation ceases
inhibits bladder contraction
11
Q

adrenergic agonists are drugs that mimim the effects of what drug?

what receptors do these drugs act on?

A

NE
Epi

alpha and beta receptors

12
Q

these are the organ system effects of what receptors?

most vascular smooth muscle

vasoconstriction, what is the effect on BP and HR(what mech)

A

alpha 1 receptor

increased BP
slows HR via baroreflex compensatory mechanism

13
Q

these are the organ system effects of what receptors?

increased HR, chronotropy, inotropy

A

beta 1 receptor

14
Q

these are the organ system effects of what receptors?

respiratory and uterine smooth muscle, skeletal muscle-relaxation/vasodilation

A

beta 2 receptor

15
Q

what is a drugs selectivity for a receptor dependent on? effects?

A

concentration

level of receptor expression in the tissue

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