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PHAR 557 > ADHD > Flashcards

ADHD Flashcards

1
Q

T or F: TV/video games cause ADHD

A

F

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2
Q

T or F: Too many ppl are being dx’ed w/ ADHD.

A

F

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3
Q

What percentage of children w/ ADHD have at least 1 comorbid condition?

A

50-90%

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4
Q

T or F: There’re genetic and environmental factors in ADHD development.

A

T

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5
Q

When is ADHD dx met according to the DSM V?

A

When six of nine of listed sx’s in EITHER the inattentiveness category OR hyperactivity/impulsivity category are met for at least 6 mths

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6
Q

Which is more efficacious for tx’ing core ADHD sx’s?

  1. behavioural tx
  2. pharmacotx
  3. both
A
  1. pharmacotx (for the core ADHD sx’s)
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7
Q

Which is more efficacious for tx’ing 2ndary outcomes in ADHD pts?

  1. behavioural tx
  2. pharmacotx
  3. both
A
  1. both
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8
Q

Which drug is Health Can-approved for ADHD monotx?

A

atomoxetine

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9
Q

According to CADDRA guidelines, which stimulant(s) are considered 1st line?

A

Long-acting fmlations of stimulant meds (methylphenidate or amphetamine)

  1. amphetamine mixed salts (Adderall XR)
  2. lisdexamfetamine (Vyvanse)
  3. methylphenidate controlled-release (Biphentin)
  4. methylphenidate extended-release (Concerta)
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10
Q

What is the interaction b/w carbamazepine and methylphenidate?

A

Carb induces 3A4
Methylphenidate is partly metabolized by 3A4

–>Reduced methylphenidate effectiveness

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11
Q

3 hallmarks of ADHD?

A
  1. inattention
  2. hyperactivity
  3. impulsivity
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12
Q

T or F: ADHD is the most treatable mental health condition

A

T

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13
Q

T or F: Attention probs of ADHD decline with time in adolescents.

A

F

Hyperactivity declines with time in adolescents

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14
Q

T or F: Pharm tx alone for ADHD is better than behavioural tx alone.

A

T

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15
Q

What is the reason for clinical differences observed when some brand name ADHD meds are changed to bioequivalent generics?

A

Diffs in Tmax b/w the two drugs

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16
Q

What do the stimulants used for ADHD tx do to help relieve sx’s? (i.e. MOA)

A

they increase intrasynaptic DA and NE (methylphenidate and amphetamine derivatives) and increase release of presynaptic catecholamines (amphetamine derivatives)

17
Q

MOA of atomoxetine

A

Selective NE reuptake inhibitor > reduces ADHD sx’s and reduces tic severity

18
Q

MOA of guanfacine

A

alpha-2 adrenergic agonist > reduced ADHD sx’s and tics

19
Q

What drug may be considered as adjunctive tx in ADHD pts, esp. if they suffer from depression?

A

Bupropion

20
Q

T or F: Clonidine is less effective than guanfacine XR for ADHD tx

A

T

21
Q

T or F: Sleep issues are common for children suffering from ADHD

A

T

22
Q

What’s the only OTC med that’s been shown to be safe and effective for tx of insomnia in children w/ ADHD?

A

melatonin

PHAR 557 (36 decks)

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