6.2.4: Carbon–carbon bond formation Flashcards
1
Q
What type of mechanism is involved in the reaction between haloalkanes and cyanide ions?
A
Nucleophilic substitution
2
Q
What type of reaction is involved in the reaction between carbonyl compounds and cyanide ions?
A
Nucleophilic addition
3
Q
How can you form a carboxylic acid from a nitrile?
A
Acid hydrolysis
4
Q
What type of catalyst is used for a Friedel-Crafts
reaction?
A
A halogen carrier (e.g. AlCl3)
5
Q
Write an equation to form an electrophile that could
be used to acylate benzene, starting with AlCl3 and RCOCl.
A
AlCl3 + RCOCl → AlCl4- + RCO+ (+ on C)
RCO+ can attack benzene
6
Q
How could you use a Friedel-Crafts mechanism to
add a methyl group to a benzene ring?
A
Use a halogenoalkane and AlCl3 to create an electrophile that can attack benzene
