What is the flow chart for gram negative organisms?
What is true about N. gonorrhoeae and its presence in humans?
Strict human pathogen
Which pts infected with N. Gon will be symptomatic?
What are some of the clinical manifestations of disseminated N. Gon?
Infection of skin
Infection of joints
Neonatae: opthalmia neonatorum
What are the two ways N. gon has variation in pili? (This prevent the production of an effective vaccine)
Antigenic variation: variable carboxy termini
Phase variation: pilin expression (on/off)
How does N. gon acquire iron from its host?
Transferrin, lactoferrin, and hemoglobin-binding proteins
Draw a diagram of the pathogenesis of N. gon
Gram stain is very sensitive and specific in which subset of the population? What other tests must be run in other subsets of the population?
Culture must done for all other groups to rule out N. gon
When do you start rx in pt with N. meningidis?
Start rx based on clinical suspicion
What are the two vaccines given for N. meningidis?
Hib-MenCY (C, Y, Hib+, tetanus toxoid) - 6 wks to 18 mo
MenACWY (A,C,W,Y) - 2-55 yr olds
What is most common serogroup of N. menin causing meningitis in the US population?
Tell me about E. corrodens?
Digame sobre Aggregatibacter
Tell me about K. kingae
Tell me about capnocytophaga
Que es Pasteurella