Give some causes of respiratory acidosis (3)
- Drug overdose
- Severe COPD
- Head injuries/neurological/muscle disease (anything reducing lung movement)
Give some causes of respiratory alkalosis (2)
- Panic attack
- Hyperventilation due to low O2 levels eg pulmonary embolism
Give some causes of metabolic acidosis
- Diabetic ketoacidosis
- Lactic acidosis (eg due to septic. shock)
- Excessive diarrhoea (loss of bicarbonate)
Useful: how kidney regulates bicarbonate and hydrogen ion concentrations
In what circumstances might an increased anion gap be seen? (3)
What changes (parameters) are peripheral chemoreceptors sensitive to and what changes are central chemoreceptors sensitive to?
The respiratory centres in the brainstem are sensitive to inputs from central and peripheral chemoreceptors. What other inputs are there into the respiratory centre?