2016 I&I Flashcards

1
Q

Immunoglobulin that passes through breast milk?

a) IgA
b) IgM
c) IgD
d) IgG

A

a) IgA

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2
Q

How do cytotoxic T cells kill virus-infected cells?

a) Apoptosis
b) Complement-dependent lysis
c) Receptor-mediated endocytosis
d) Cytotoxic antibodies

A

a) Apoptosis

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3
Q

Which technique is best suited for identifying cell surface antigen in tissues?

a) precipitation
b) immunofluorescence
c) flow cytometry
d) agglutination

A

b) immunofluorescence

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4
Q

What does flow cytometry detect?

a) agglutination reaction
b) cytotoxicity of target cell
c) antigen on cell surface
d) precipitation

A

c) antigen on cell surface

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5
Q

When thymocytes enter the thymus they express

a) TCR
b) MHC1
c) MHC2
d) CD2

A

a) TCR

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6
Q

Which of the following bacteria produce Extended-spectrum B-lactamases (ESBLs)?

a. K. pneumoniae
b. S. aureus

A

a. K. pneumoniae ( included in OXA-type beta-lactamases)

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7
Q

Which vaccine is recommended for healthcare workers?

a. Hepatitis C
b. Hepatitis E
c. Influenza
d. Norwalk vaccine

A

c. Influenza

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8
Q

A toddler has a chronic mild diarrhea. He needed a blood transfusion and developed an anaphylactic reaction to it. Which immunodeficiency disease does he have?

a. Selective IgA deficiency
b. X-linked agammaglobulinemia
c. SCID
d. chronic granulomatous disease

A

a. Selective IgA deficiency

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9
Q

What does the basic reproductive number represent?

a) The number of susceptible people who get the infection at the end of epidemic period
b) The number of cases generated by a single case if no one is immune
c) The number of people die from infection at the end of infectious period
d) The number of cases generated during the epidemic if no one is immune

A

b)The number of cases generated by a single case if no one is immune

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10
Q

What lymph organ has elongated cells?

a) spleen
b) thymus
c) lymph node
d) appendix

A

a) spleen

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11
Q

What is the flow direction of lymph in lymph nodes?

a) Afferent vessels - medullary sinus - efferent vessels
b) Efferent vessels - trabecular sinus - medullary sinus
c) sub capsular sinus - trabecular sinus - efferent vessels
d) trabecular sinus - medullary sinus - efferent vessels

A

d) trabecular sinus - medullary sinus - efferent vessels

full flow process= afferent vessel – subcapsular sinus – trabecular sinus – medullary sinus – efferent vessel

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12
Q

what is the mechanism of clavulanic acid?

a) inhibition of B-lactamases
b) inhibition of folate synthesis
c) inhibition of ribosomal subunit assembly
d) inhibition of transpeptidase

A

a) inhibition of B-lactamases

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13
Q

Which best describes Maraviroc?

a) inhibit the entry of HIV virus
b) stop DNA coding, RNA translate

A

a) inhibit the entry of HIV virus

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