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Final Exams - 2nd year > 2012 biochem > Flashcards

2012 biochem Flashcards

1
Q

Which is the following is the most common in human genome?

A

Alu family

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2
Q

Which of the following activates pentose phosphate pathway?

A

NAD+

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3
Q

What is the cofactor associated for cross-linkage collagen?

a. Vitamin C
b. Copper

A

b. Copper

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4
Q

Which amino acid is found in every protein?

a. methionine
b. valine
c. glycine

A

a. methionine

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5
Q

Which vitamin contributes to collagen bone sheath?

A

Vit D

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6
Q

An enzyme follows Michaelis-Mentin method, what would happen if a competitive inhibitor drug is present?

a. lower km
b. higher km
c. lower vmax

A

b. higher km

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7
Q

What is the cause of sickle cell anemia?

A

Gene mutation

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8
Q

Where in the cell is glycogen found?

A

cytoplasm

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9
Q

HMG CoA reductase is the rate limiting step of which of the following?

a. nitrogen disposal
b. bile acid synthesis
c. cholesterol synthesis

A

c. cholesterol synthesis

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10
Q

What happens to the tumor suppressor gene during cancer?

a. mutation
a. activation

A

a. mutation

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11
Q

Where is desaturase found in the cell?

A

ER

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12
Q

What is the function of dNTP?

A

Support the PCR (DNA synthesis)

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13
Q

What is the final step of DNA replication?

A

DNA ligase seals the fragments of newly synthesized DNA

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14
Q

What is the immediate precursor of ketone bodies?

A

Acetyl CoA

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15
Q

What does the brain use in addition to glucose in prolonged starvation?

A

Ketone bodies

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16
Q

What is the main source for energy for the liver?

A

Glycogen

17
Q

What issued for mRNA stability during splicing?

A

Iron

18
Q

What is a characteristic of the cell membrane?

A

Amphipathic

19
Q

What causes Cystic fibrosis?

A

Phe 508 deletion

20
Q

Which of the following is considered ribozyme?

A

RNase p

21
Q

What is a characteristic of Tf IID?

a. Transcription factor
b. Regulatory protein

A

b. Regulatory protein

22
Q

What does the AG change?

A

direction (of reaction)

23
Q

Which of the following is true about PFK in the heart?

A

It’s phosphorylated in the heart

24
Q

What activates TCA cycle?

A

NAD+

25
Q

If a person ate a protein-rich (NAG) meal, what happens?

a. nitrogen balance
b. nitrogen imbalance

A

a. nitrogen balance

26
Q

What does Malonyl-CoA inhibit?

A

Carnitine acyltransferase-1

27
Q

if a person has high cholesterol levels in the blood what is the cause?

A

LDL receptor

28
Q

What is the main lipid in membrane?

A

Sphingolipid

Final Exams - 2nd year (31 decks)

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