19. General pathology Flashcards Preview

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1

Indicates that an antigen(antibody generating) is present

Inflammation

2

Redness

Rubor

3

Heat

Calor

4

Pain

Dolor

5

Swelling

Tumor

6

Loss of function

Function laesa

7

They cause vasodilation and increase in vascular permeability

Mediators of inflammation
- prostaglandin, bradykinin, kallidin
- histamine
- lymphocytes
- wbc enzymes

8

Mediators of inflammation that produces PAIN

Prostaglandins
Bradykinin
Kallidin

9

Most important mediator of inflammation

Histamine

10

Cells that produces histamine

Mast cells
Eosinophils
Basophils
Platelets

11

Opp fxn of histamine
Histamine = vasodilation

Serotonin = vasoconstriction

12

H1 receptors

Bronchi - bronchoconstriction
Bv - vasodilation

13

H2 receptors

Stomach - increase HCl acid

14

H3 receptors

Cns

15

BQ: Dse assoc with ⬇️ T cell count in Thymus and ⬇️ PTH in Parathyroid gland

DiGeorge Syndrome

16

BQ: DiGeorge Syndrome = ⬇️ PTH
- Hypoparathyroidism
-Hypocalcemia
==

Tetany
- chvostek and trosseous sign

17

What is the disease associated with ⬇️ B cell count?

Bruton’s agammaglobulinemia

18

Matured in thymus

T lymphocytes

19

T helper cell

CD4

20

Cytotoxic T cell

CD8

21

Specialized CD8

NK cells

22

Matures in bone marrow

B lymphocytes

23

Activated B cells ; produces immunoglobulins

Plasma cells

24

Effects of vascular permeability

Escape of plasma contents towards interstitial tissues

25

Numerous proteins (albumin)
Seen in ABSCESS

Exudate

26

Few protein (albumin)
Seen in EDEMA(pitting or non pitting) and gingival crevicular fluid/sulcular fluid

Transudate

27

Specific gravity of exudate

> 1.018

28

Specific gravity of Transudate

< 1.012

29

Peripherally lining up of WBCs
Preparation for diapedesis

Pavementing or Migration

30

BQ: What is the passive movement of blood cells across endothelial wall?

Diapedesis
- (after mag line up ng wbc sa periphery or pavementing, magmmove yung wbc across endothelial wall or endothelium which is the wall of the blood vessel because antigen is outside the blood vessel or at the surface)