19 - 3 Parent Babies Flashcards Preview

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Flashcards in 19 - 3 Parent Babies Deck (8)
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1
Q

What is the theory explaining mitochondria in cells?

A

Endosymbiotic theory

2
Q

What are clinical presentations of mitochondrial disease?

A
  • Weakness
  • Fatigue
  • Spasms and seizures
  • Inability to put weight on
  • Hearing loss
  • Elevated lactate
  • Autism
  • Developmental delay
3
Q

What are the features of a family history of mitochondrial disease?

A
  • Similar pattern to autosomal recessive
  • Look at maternal line
4
Q

Why are some people affected more by mitochondrial disease?

A
  • Different ratios of healthy to faulty mitochondria
  • Depending on how meiosis occur, the number of mitochondria in each gamete varies
5
Q

What is the prognosis for mitochondrial disease?

A
  • Progressive weakness
  • Death
  • Flares up and down
6
Q

What are the five ethical approaches and what is an ethical framework?

A
7
Q

What are ethical issues involved with three parent babies?

A
8
Q

What are the two ways of carrying out 3 parent babies?

A
  • Has to be done in proper IVF lab
  • Has to be developed here or people will want to go to other countries to do it